Literature DB >> 12176256

Biodegradation and drug release studies of BSA loaded gelatin microspheres.

K Mladenovska1, E Kumbaradzi, G Dodov, L Makraduli, K Goracinova.   

Abstract

Certain variations in the process parameters (emulsification time, surfactant concentration) were performed in order to prepare BSA-loaded gelatin microspheres with high loading efficacy and particle size ranging from 1 to 10 microm using a procedure originally employed by Tabata and Ikada. The mathematical modelling of drug release in the presence of collagenase showed a biphasic release pattern, where the rate constant for the initial time release confirmed the influence of the particle size and/or enzymatic degradation rate on drug release rate.

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Year:  2002        PMID： 12176256     DOI： 10.1016/s0378-5173(02)00167-9

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  10 in total

1.  Producing gelatin nanoparticles as delivery system for bovine serum albumin.

Authors:  Bahareh Azimi; Parviz Nourpanah; Mohammad Rabiee; Shahram Arbab
Journal:  Iran Biomed J       Date:  2014

Review 2.  Biopolymeric nanoparticles.

Authors:  Sushmitha Sundar; Joydip Kundu; Subhas C Kundu
Journal:  Sci Technol Adv Mater       Date:  2010-02-26       Impact factor: 8.090

3.  Injectable Macroporous Hydrogel Formed by Enzymatic Cross-Linking of Gelatin Microgels.

Authors:  Shujie Hou; Rachel Lake; Shiwha Park; Seth Edwards; Chante Jones; Kyung Jae Jeong
Journal:  ACS Appl Bio Mater       Date:  2018-10-15

4.  Mathematical modelling of glycosaminoglycan production by stem cell aggregates incorporated with growth factor-releasing polymer microspheres.

Authors:  Andrew S Fu; Loran D Solorio; Eben Alsberg; Gerald M Saidel
Journal:  J Tissue Eng Regen Med       Date:  2014-07-22       Impact factor: 3.963

5.  Permeability mapping of gelatin methacryloyl hydrogels.

Authors:  Amir K Miri; Hossein Goodarzi Hosseinabadi; Berivan Cecen; Shabir Hassan; Yu Shrike Zhang
Journal:  Acta Biomater       Date:  2018-07-04       Impact factor: 8.947

6.  Gelatin Promotes Cell Retention Within Decellularized Heart Extracellular Matrix Vasculature and Parenchyma.

Authors:  Karis R Tang-Quan; Yutao Xi; Camila Hochman-Mendez; Qian Xiang; Po-Feng Lee; Luiz C Sampaio; Doris A Taylor
Journal:  Cell Mol Bioeng       Date:  2020-07-27       Impact factor: 2.321

Review 7.  Methods to assess in vitro drug release from injectable polymeric particulate systems.

Authors:  Susan S D'Souza; Patrick P DeLuca
Journal:  Pharm Res       Date:  2006-01-13       Impact factor: 4.580

8.  Development and characterization of gelatin based nanoparticles for targeted delivery of zidovudine.

Authors:  Namdeo R Jadhav; Jadhav S Tone; Preeti V Irny; Sameer J Nadaf
Journal:  Int J Pharm Investig       Date:  2013-07

Review 9.  Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates.

Authors:  Suhair Al-Nimry; Alaa Abu Dayah; Inas Hasan; Rawand Daghmash
Journal:  Mar Drugs       Date:  2021-03-08       Impact factor: 5.118

Review 10.  Multiparametric Material Functionality of Microtissue-Based In Vitro Models as Alternatives to Animal Testing.

Authors:  Elena Stengelin; Julian Thiele; Sebastian Seiffert
Journal:  Adv Sci (Weinh)       Date:  2022-01-18       Impact factor: 16.806
  10 in total

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