Literature DB >> 12175712

Primipaternity and duration of exposure to sperm antigens as risk factors for pre-eclampsia.

G R Verwoerd1, D R Hall, D Grové, J S Maritz, H J Odendaal.   

Abstract

OBJECTIVE: To establish whether primipaternity and duration of unprotected sexual cohabitation is associated with an increased risk of pre-eclampsia.
METHOD: At a tertiary referral center, the study had a case and control group of 60 multigravid women each, as well as a case and control group of 50 primigravid women each. Information was compiled by means of a confidential questionnaire. RESULT: After multiple logistic regression analysis using age, smoking, hypertension in previous pregnancies, change of paternity and duration of unprotected sexual cohabitation as predictors, the regression coefficients for change of paternity and sexual cohabitation of longer than 6 months in multigravid women were -0.4 (P = 0.15) and -1.4 (P = 0.03), respectively.
CONCLUSION: Multigravid women with a period of unprotected sexual cohabitation of longer than 6 months had a decreased risk of pre-eclampsia. Primipaternity was not a significant risk factor for pre-eclampsia.

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Year:  2002        PMID: 12175712     DOI: 10.1016/s0020-7292(02)00130-3

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  4 in total

1.  Genetic recapitulation of human pre-eclampsia risk during convergent evolution of reduced placental invasiveness in eutherian mammals.

Authors:  Michael G Elliot; Bernard J Crespi
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-03-05       Impact factor: 6.237

2.  The effect of short duration sperm exposure on development of preeclampsia in primigravid women.

Authors:  Z Sadat; M Abedzadeh Kalahroudi; F Saberi
Journal:  Iran Red Crescent Med J       Date:  2012-01-01       Impact factor: 0.611

3.  Soluble HLA-G levels in seminal plasma are associated with HLA-G 3'UTR genotypes and haplotypes.

Authors:  Moniek H C Craenmehr; Geert W Haasnoot; Jos J M Drabbels; Marijke J Spruyt-Gerritse; Milo Cao; Carin van der Keur; Johanna M Kapsenberg; Merve Uyar-Mercankaya; Els van Beelen; Tess Meuleman; Marie-Louise P van der Hoorn; Sebastiaan Heidt; Frans H J Claas; Michael Eikmans
Journal:  HLA       Date:  2019-08-08       Impact factor: 4.513

Review 4.  Inter-pregnancy interval and risk of recurrent pre-eclampsia: systematic review and meta-analysis.

Authors:  Gabriela Cormick; Ana Pilar Betrán; Agustín Ciapponi; David R Hall; G Justus Hofmeyr
Journal:  Reprod Health       Date:  2016-07-18       Impact factor: 3.223

  4 in total

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