Literature DB >> 12175677

Insulin-like growth factor-II induces hypertrophy of adult cardiomyocytes via two alternative pathways.

Chih-Yang Huang1, Ling-Yang Hao, Dennis E Buetow.   

Abstract

Insulin-like growth factor (IGF)-II is known to induce hypertrophy of isolated adult rat ventricular cardiomyocytes cultured in the absence of serum. However, it is not known how the growth factor exerts this hypertrophic effect. We show here that IGF-II induces hypertrophy of the cultured cardiomyocytes via two alternative pathways: (1) an IGF-I receptor-dependent pathway, or (2) a lysosome-dependent pathway when the IGF-I receptor-dependent pathway is blocked. Copyright 2002 Elsevier Science Ltd.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12175677     DOI： 10.1006/cbir.2002.0919

Source DB:  PubMed          Journal:  Cell Biol Int        ISSN： 1065-6995            Impact factor:   3.612


  10 in total

1.  Cross-talk between MAPKs and PI-3K pathways alters the functional density of I(K) channels in hypertrophied hearts.

Authors:  Aiqiu Zhao; Zikiar Alvin; Graham Laurence; Chuanfu Li; Georges E Haddad
Journal:  Ethn Dis       Date:  2010       Impact factor: 1.847

2.  Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency.

Authors:  Anna Polesskaya; Sylvain Cuvellier; Irina Naguibneva; Arnaud Duquet; Eric G Moss; Annick Harel-Bellan
Journal:  Genes Dev       Date:  2007-05-01       Impact factor: 11.361

3.  Parent-of-origin effects on cardiac response to pressure overload in mice.

Authors:  Cordelia J Barrick; Anping Dong; Rebekah Waikel; Drew Corn; Fanmuyi Yang; David W Threadgill; Susan S Smyth
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-06-26       Impact factor: 4.733

4.  Regulation of cardiomyocyte Glut4 expression by ZAC1.

Authors:  Michael P Czubryt; Lise Lamoureux; Angela Ramjiawan; Bernard Abrenica; Jaganmohan Jangamreddy; Kristin Swan
Journal:  J Biol Chem       Date:  2010-04-02       Impact factor: 5.157

5.  Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb.

Authors:  Kimberley C W Wang; Lei Zhang; I Caroline McMillen; Kimberley J Botting; Jaime A Duffield; Song Zhang; Catherine M Suter; Doug A Brooks; Janna L Morrison
Journal:  J Physiol       Date:  2011-08-01       Impact factor: 5.182

6.  Dung-Shen Downregulates the Synergistic Apoptotic Effects of Angiotensin II Plus Leu 27-IGF II on Cardiomyoblasts.

Authors:  Ko-Shih Chang; Nien-Hung Lee; Wei-Wen Kuo; Wei-Syun Hu; Mu-Hsin Chang; Fuu-Jen Tsai; Kun-Hsi Tsai; Yuh-Shyong Yang; Tung-Sheng Chen; Chih-Yang Huang
Journal:  Acta Cardiol Sin       Date:  2014-01       Impact factor: 2.672

7.  Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?

Authors:  Xiang Wang; Ana-Maria Bosonea; Jeffrey Odenbach; Carlos Fernandez-Patron
Journal:  Curr Hypertens Rev       Date:  2012-08-01

8.  Basal and IGF-I-dependent regulation of potassium channels by MAP kinases and PI3-kinase during eccentric cardiac hypertrophy.

Authors:  Leyla Y Teos; Aiqiu Zhao; Zikiar Alvin; Graham G Laurence; Chuanfu Li; Georges E Haddad
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-08-29       Impact factor: 4.733

9.  Effects of IGF-1 on I(K) and I(K1) Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes.

Authors:  Richard M Millis; Zikiar V Alvin; Aiqiu Zhao; Georges E Haddad
Journal:  Int J Cell Biol       Date:  2012-06-18

10.  Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death.

Authors:  Chih-Yang Huang; Wei-Wen Kuo; Jeng-Fan Lo; Tsung-Jung Ho; Pei-Ying Pai; Shu-Fen Chiang; Pei-Yu Chen; Fu-Jen Tsai; Chang-Hai Tsai; Chih-Yang Huang
Journal:  Cell Death Dis       Date:  2016-11-03       Impact factor: 8.469
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.