BACKGROUND: Dowling-Degos disease is a rare condition with a genetically determined disturbance of epidermal proliferation. The typical clinical picture is a reticulate pigmentation of the flexures, genital folds, and pectoral skin areas. Many different treatment options have been tried in recent years without a convincing therapeutic benefit. OBJECTIVE: To determine the effectiveness of Er:YAG laser in Dowling-Degos disease. METHODS: A 44-year-old woman suffering from Dowling-Degos disease was treated with the Er:YAG laser pulse energy between 1,000 and 1,200 mJ, three consecutive passes. RESULTS: The laser treatment led to a good clinical result. CONCLUSION: Our case suggest that treatment with the Er:YAG laser might be a successful strategy in Dowling-Degos disease.
BACKGROUND:Dowling-Degos disease is a rare condition with a genetically determined disturbance of epidermal proliferation. The typical clinical picture is a reticulate pigmentation of the flexures, genital folds, and pectoral skin areas. Many different treatment options have been tried in recent years without a convincing therapeutic benefit. OBJECTIVE: To determine the effectiveness of Er:YAG laser in Dowling-Degos disease. METHODS: A 44-year-old woman suffering from Dowling-Degos disease was treated with the Er:YAG laser pulse energy between 1,000 and 1,200 mJ, three consecutive passes. RESULTS: The laser treatment led to a good clinical result. CONCLUSION: Our case suggest that treatment with the Er:YAG laser might be a successful strategy in Dowling-Degos disease.
Authors: Regina C Betz; Laura Planko; Sibylle Eigelshoven; Sandra Hanneken; Sandra M Pasternack; Heinrich Bussow; Kris Van Den Bogaert; Joerg Wenzel; Markus Braun-Falco; Arno Rutten; Michael A Rogers; Thomas Ruzicka; Markus M Nöthen; Thomas M Magin; Roland Kruse Journal: Am J Hum Genet Date: 2006-01-19 Impact factor: 11.025