| Literature DB >> 12174 |
Abstract
A new ribonuclease called RNase N was isolated from Escherichia coli. It is a nonspecific endoribonuclease that can cleave rRNA, poly(U), and poly(C) to small oligonucleotides and 5'-mononucleotides. It requires monovalent cations and is inhibited by divalent cations. It is suggested that this enzyme plays a role in the decay of rRNA,under various starvation conditions and perhaps in the decay of mRNA.Entities:
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Year: 1976 PMID： 12174
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157