| Literature DB >> 12173767 |
G Elia1, N Decaro, A Tinelli, V Martella, A Pratelli, C Buonavoglia.
Abstract
We investigated by Western Blotting the antibody responses against the three major structural proteins of Canine coronavirus (CCoV) in dogs naturally infected. A pool of Elisa positive sera were also tested to clearly identify the binding profiles of CCoV proteins. The immune response to S protein was barely detectable in naturally infected dogs, whereas anti-M and anti-N antibodies were detected with a very strong reaction and for a long time post infection. The limited response to S protein may explain the poor protection of dogs and the possibility of persisting infection.Entities:
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Year: 2002 PMID： 12173767
Source DB: PubMed Journal: New Microbiol ISSN： 1121-7138 Impact factor: 2.479