Literature DB >> 12173704

Recurrent pneumococcal meningitis in homozygous C3 deficiency.

Mehmet Totan1.   

Abstract

Congenital deficiencies of complement system proteins are rare. A 4-year-old girl was admitted for meningitis. She had had repeated attacks of pneumococcal meningitis and otitis media at the age of 3 years. Analysis of cerebrospinal fluid showed that this meningitis was due to pneumococcal infection. Complement 3 and CH50 values of the proband and her brother were low, while her parents were normal. The patient was given polyvalent pneumococcal and anti-haemophilus vaccines plus ceftriaxone. Recovery was complete after 15 days of antibiotic therapy. This is the first description of a case of recurrent meningitis with C3 and CH50 deficiency in a Turkish family.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12173704     DOI： 10.1007/bf02722692

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN： 0019-5456            Impact factor:   1.967


  5 in total

1.  Development of systemic lupus erythematosus in a patient with selective complete C1q deficiency.

Authors:  A I Berkel; F Petry; O Sanal; K Tinaztepe; F Ersoy; A Bakkaloglu; M Loos
Journal:  Eur J Pediatr       Date:  1997-02       Impact factor: 3.183

2.  An association between homozygous C3 deficiency and low levels of anti-pneumococcal capsular polysaccharide antibodies.

Authors:  M A Hazlewood; D S Kumararatne; A D Webster; M Goodall; P Bird; M Daha
Journal:  Clin Exp Immunol       Date:  1992-03       Impact factor: 4.330

3.  [C2 deficiency discovered in pneumococcal meningitis].

Authors:  M Monfort-Gouraud; M A Le Gall; F Nicot; J Badoual
Journal:  Arch Fr Pediatr       Date:  1993-02

4.  Recurrent meningococcal infections in a patient with congenital C5 deficiency.

Authors:  A Bols; J Janssens; W Peetermans; E Stevens; H Bobbaers
Journal:  Acta Clin Belg       Date:  1993       Impact factor: 1.264

Review 5.  C1q and systemic lupus erythematosus.

Authors:  M J Walport; K A Davies; M Botto
Journal:  Immunobiology       Date:  1998-08       Impact factor: 3.144
  5 in total
  6 in total

Review 1.  Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis.

Authors:  Marc Tebruegge; Nigel Curtis
Journal:  Clin Microbiol Rev       Date:  2008-07       Impact factor: 26.132

Review 2.  The genetic basis of pneumococcal and staphylococcal infections: inborn errors of human TLR and IL-1R immunity.

Authors:  Bertrand Boisson
Journal:  Hum Genet       Date:  2020-01-24       Impact factor: 4.132

3.  IRAK4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease.

Authors:  Cheng-Lung Ku; Capucine Picard; Melinda Erdös; Axel Jeurissen; Jacinta Bustamante; Anne Puel; Horst von Bernuth; Orchidée Filipe-Santos; Huey-Hsuan Chang; Tatiana Lawrence; Marc Raes; László Maródi; Xavier Bossuyt; Jean-Laurent Casanova
Journal:  J Med Genet       Date:  2006-09-01       Impact factor: 6.318

Review 4.  Infections of people with complement deficiencies and patients who have undergone splenectomy.

Authors:  Sanjay Ram; Lisa A Lewis; Peter A Rice
Journal:  Clin Microbiol Rev       Date:  2010-10       Impact factor: 26.132

Review 5.  Complement Has Brains-Do Intracellular Complement and Immunometabolism Cooperate in Tissue Homeostasis and Behavior?

Authors:  Natalia Kunz; Claudia Kemper
Journal:  Front Immunol       Date:  2021-02-25       Impact factor: 7.561

6.  A Retrospective Study of Recurrent Bacterial Meningitis in Children: Etiology, Clinical Course, and Treatment.

Authors:  Xin Li; Hua-Zhang Liu; Ling-Yu Pang; Xin Wen; Su-Zhen Sun
Journal:  Comput Math Methods Med       Date:  2022-03-10       Impact factor: 2.238
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.