Literature DB >> 12171580

Chemotherapeutic agents against malaria: what next after chloroquine?

José N Domínguez1.   

Abstract

This is a general review of currently available antimalarial drugs, these compounds are gathered according with its chemical structure and the biological targets. A great number of these new antimalarial agents are now moving actively in the pipeline from basic science to clinical studies.

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Year:  2002        PMID： 12171580     DOI： 10.2174/1568026023392986

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  4 in total

1.  Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas.

Authors:  Kekeli Ekoue-Kovi; Kimberly Yearick; Daniel P Iwaniuk; Jayakumar K Natarajan; John Alumasa; Angel C de Dios; Paul D Roepe; Christian Wolf
Journal:  Bioorg Med Chem       Date:  2008-11-12       Impact factor: 3.641

2.  Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain.

Authors:  Daniel P Iwaniuk; Eric D Whetmore; Nicholas Rosa; Kekeli Ekoue-Kovi; John Alumasa; Angel C de Dios; Paul D Roepe; Christian Wolf
Journal:  Bioorg Med Chem       Date:  2009-08-08       Impact factor: 3.641

3.  Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines.

Authors:  Kimberly Yearick; Kekeli Ekoue-Kovi; Daniel P Iwaniuk; Jayakumar K Natarajan; John Alumasa; Angel C de Dios; Paul D Roepe; Christian Wolf
Journal:  J Med Chem       Date:  2008-03-18       Impact factor: 7.446

4.  Discovery and optimisation studies of antimalarial phenotypic hits.

Authors:  Alka Mital; Dinakaran Murugesan; Marcel Kaiser; Clive Yeates; Ian H Gilbert
Journal:  Eur J Med Chem       Date:  2015-09-09       Impact factor: 6.514
  4 in total

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