Literature DB >> 12167585

A prospective evaluation of patients undergoing surgery for the palliation of an advanced malignancy.

Thomas J Miner1, David P Jaques, Craig D Shriver.   

Abstract

BACKGROUND: Decisions regarding the use of surgical procedures for the palliation of symptoms caused by advanced malignancies require the highest level of surgical judgment. Prospective analysis of palliative surgical care may facilitate a more effective and representative evaluation of these patients.
METHODS: Patients requiring surgery planned solely for the palliation of an advanced malignancy were offered entry onto this study. Outcome measurements were made before surgery and monthly thereafter until the patient's death. Accepted techniques of pain assessment, quality of life, and functional status were used.
RESULTS: Between May 1997 and December 1999, 26 patients were enrolled. Although 46% (12 of 26) of patients demonstrated improvement in pain control or quality of life after palliative surgery, these benefits lasted a median of only 3.4 months. Palliative surgery was associated with significant postoperative complications in 35% (9 of 26) patients.
CONCLUSIONS: Although many patients had no apparent demonstrable benefit from surgery, surgeons were able to identify a group of patients who experienced significant benefits after a palliative procedure. The relationships between the patient and family members and the surgeon play an important role in decision-making throughout the palliative phase of cancer treatment.

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Mesh:

Year:  2002        PMID: 12167585     DOI: 10.1007/bf02574487

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  16 in total

1.  Clinical outcomes with laparoscopic stage M1, unresected gastric adenocarcinoma.

Authors:  Abeezar I Sarela; Thomas J Miner; Martin S Karpeh; Daniel G Coit; David P Jaques; Murray F Brennan
Journal:  Ann Surg       Date:  2006-02       Impact factor: 12.969

Review 2.  Current role of surgical therapy in gastric cancer.

Authors:  Ryan Swan; Thomas J Miner
Journal:  World J Gastroenterol       Date:  2006-01-21       Impact factor: 5.742

3.  Value of nonpalliative resection as a therapeutic and pre-emptive operation for metastatic gastric cancer.

Authors:  Seong-Heum Park; Jong-Han Kim; Joong-Min Park; Sung-Soo Park; Seung-Joo Kim; Chong-Suk Kim; Young-Jae Mok
Journal:  World J Surg       Date:  2009-02       Impact factor: 3.352

Review 4.  Multimodal treatment of gastric cancer in the west: Where are we going?

Authors:  Daniele Marrelli; Karol Polom; Giovanni de Manzoni; Paolo Morgagni; Gian Luca Baiocchi; Franco Roviello
Journal:  World J Gastroenterol       Date:  2015-07-14       Impact factor: 5.742

5.  Surgical and Survival Outcome Following Truly Palliative Gastrectomy in Patients with Incurable Gastric Cancer.

Authors:  Masanori Tokunaga; Rie Makuuchi; Yuichiro Miki; Yutaka Tanizawa; Etsuro Bando; Taiichi Kawamura; Masanori Terashima
Journal:  World J Surg       Date:  2016-05       Impact factor: 3.352

6.  Long-term survival following treatment of pseudomyxoma peritonei: an analysis of surgical therapy.

Authors:  Thomas J Miner; Jinru Shia; David P Jaques; David S Klimstra; Murray F Brennan; Daniel G Coit
Journal:  Ann Surg       Date:  2005-02       Impact factor: 12.969

7.  A prospective evaluation of the durability of palliative interventions for patients with metastatic breast cancer.

Authors:  Mary Morrogh; Thomas J Miner; Anna Park; Ann Jenckes; Mithat Gonen; Andrew Seidman; Monica Morrow; David P Jaques; Tari A King
Journal:  Cancer       Date:  2010-07-15       Impact factor: 6.860

8.  A prospective, symptom related, outcomes analysis of 1022 palliative procedures for advanced cancer.

Authors:  Thomas J Miner; Murray F Brennan; David P Jaques
Journal:  Ann Surg       Date:  2004-10       Impact factor: 12.969

Review 9.  Palliative surgery for malignant bowel obstruction from carcinomatosis: a systematic review.

Authors:  Terrah J Paul Olson; Carolyn Pinkerton; Karen J Brasel; Margaret L Schwarze
Journal:  JAMA Surg       Date:  2014-04       Impact factor: 14.766

10.  Radical palliative surgery: new limits to pursue.

Authors:  Mindy Young-Spint; Yigit S Guner; Frederick J Meyers; Phillip Schneider; Vijay P Khatri
Journal:  Pediatr Surg Int       Date:  2009-10       Impact factor: 1.827

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