Literature DB >> 12166590

Profile of solvent abusers (glue sniffers) in East Malaysia.

M Y Zabedah1, M Razak, I Zakiah, A B Zuraidah.   

Abstract

Solvent abuse is deliberate sniffing of an organic solvent for the intention of altering the physiological state of the individual. It is also commonly known as glue sniffing because glue is the most commonly abused substance. This form of substance abuse is widespread throughout the world and usually popular among secondary school children and young adults because of its easy availability and it is cheaper compared with most drugs of abuse. In Malaysia this problem has been recognized especially among the children in East Malaysia. In this study, 37 children and young adults from or around Kota Kinabalu, Sabah were referred to Bukit Padang Psychiatric Hospital by the Anti-drug Task force for suspected solvent abuse. These children were interviewed using questionaire and examined physically. Blood and urine were analysed for toluene and hippuric acid. 27 of the children, age ranging between 8 and 20 years, willingly admitted to sniffing glue for a period between a few months to 2 years. Most of them were children of Fillipino illegal immigrants in Kota Kinabalu. Biochemical parameters were found to be normal. Two of them were pale with low hemoglobin and 7 had eosinophilia. Haematuria and proteinuria were found in 21 children (78%). 16 blood samples with toluene levels ranging from 0.3 to 41 microg/ml and 10 urine samples have elevated urinary hippuric acid levels ranging from 1.2 to 7.4 mg/ml. Strong positive correlation was noted between mean blood toluene levels and duration of abuse.

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Year:  2001        PMID: 12166590

Source DB:  PubMed          Journal:  Malays J Pathol        ISSN: 0126-8635            Impact factor:   0.656


  5 in total

1.  Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure.

Authors:  Mehmet Kanter
Journal:  J Mol Histol       Date:  2010-12-01       Impact factor: 2.611

2.  Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats.

Authors:  Mehmet Kanter
Journal:  Neurochem Res       Date:  2007-10-11       Impact factor: 3.996

3.  Protective effects of Nigella sativa on the neuronal injury in frontal cortex and brain stem after chronic toluene exposure.

Authors:  Mehmet Kanter
Journal:  Neurochem Res       Date:  2008-04-22       Impact factor: 3.996

Review 4.  Developing an evidence assessment framework and appraising the academic literature on migrant health in Malaysia: a scoping review.

Authors:  Allard Willem de Smalen; Zhie X Chan; Claudia Abreu Lopes; Michaella Vanore; Tharani Loganathan; Nicola S Pocock
Journal:  BMJ Open       Date:  2021-01-18       Impact factor: 2.692

Review 5.  Antidotal effects of thymoquinone against neurotoxic agents.

Authors:  Ali Rajabpour Sanati; Tahereh Farkhondeh; Saeed Samarghandian
Journal:  Interdiscip Toxicol       Date:  2019-03-02
  5 in total

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