Literature DB >> 12165203

Navigating the maze of complement genetics: a guide for clinicians.

Harvey R Colten1.   

Abstract

Genetic deficiencies of nearly all of the 30 complement system proteins have been recognized clinically. In many instances, the molecular basis for the deficiency has been elucidated. As a byproduct of these studies, we now have new insights into the pathophysiologic role of complement studies in several acquired diseases. New targets for drug development are among the practical outcomes of work on complement genetics.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12165203     DOI: 10.1007/s11882-002-0070-6

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN: 1529-7322            Impact factor:   4.919


  45 in total

Review 1.  Complement deficiencies.

Authors:  M M Frank
Journal:  Pediatr Clin North Am       Date:  2000-12       Impact factor: 3.278

Review 2.  Complement factors and their receptors.

Authors:  J A Ember; T E Hugli
Journal:  Immunopharmacology       Date:  1997-12

3.  Disruption of disulfide bonds is responsible for impaired secretion in human complement factor H deficiency.

Authors:  B Z Schmidt; N L Fowler; T Hidvegi; D H Perlmutter; H R Colten
Journal:  J Biol Chem       Date:  1999-04-23       Impact factor: 5.157

4.  Heterogeneity, polypeptide chain composition and antigenic reactivity of C3 nephritic factor.

Authors:  M R Daha; K F Austen; D T Fearon
Journal:  J Immunol       Date:  1978-04       Impact factor: 5.422

5.  C3 nephritic factor and C4 nephritic factor in the serum of two patients with hypocomplementaemic membranoproliferative glomerulonephritis.

Authors:  Y Tanuma; H Ohi; S Watanabe; M Seki; M Hatano
Journal:  Clin Exp Immunol       Date:  1989-04       Impact factor: 4.330

6.  Plasma bradykinin in angio-oedema.

Authors:  J Nussberger; M Cugno; C Amstutz; M Cicardi; A Pellacani; A Agostoni
Journal:  Lancet       Date:  1998-06-06       Impact factor: 79.321

7.  A role for the C3a anaphylatoxin receptor in the effector phase of asthma.

Authors:  A A Humbles; B Lu; C A Nilsson; C Lilly; E Israel; Y Fujiwara; N P Gerard; C Gerard
Journal:  Nature       Date:  2000-08-31       Impact factor: 49.962

Review 8.  C1-inhibitor deficiency and angioedema.

Authors:  A Carugati; E Pappalardo; L C Zingale; M Cicardi
Journal:  Mol Immunol       Date:  2001-08       Impact factor: 4.407

9.  Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins.

Authors:  D C Anderson; T A Springer
Journal:  Annu Rev Med       Date:  1987       Impact factor: 13.739

10.  Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

Authors:  M R Wessels; P Butko; M Ma; H B Warren; A L Lage; M C Carroll
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-05       Impact factor: 11.205

View more
  1 in total

Review 1.  The yin and the yang of early classical pathway complement disorders.

Authors:  Kathleen E Sullivan
Journal:  Clin Exp Immunol       Date:  2022-08-19       Impact factor: 5.732

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.