Literature DB >> 12164273

Sedative and anticonvulsant activities of goodyerin, a flavonol glycoside from Goodyera schlechtendaliana.

Xiao-Ming Du1, Ning-Yi Sun, Nanako Takizawa, Yong-Tian Guo, Yukihiro Shoyama.   

Abstract

Goodyerin is a flavonol glycoside isolated from the whole plants of Goodyera schlechtendaliana which has been used as a substitute for the crude drug, Anoectochilus formosanus. The pharmacological properties of goodyerin were assayed for effects on spontaneous locomotor activity, on pentobarbital-induced hypnosis, and on anticonvulsant activity against picrotoxin-induced seizures in rodents. Goodyerin exhibited a significant and dose-dependent sedative and anticonvulsant effect.

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Year:  2002        PMID： 12164273     DOI： 10.1002/ptr.862

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  6 in total

1.  Sedative and anxiolytic effects of the extracts of the leaves of Stachytarpheta cayennensis in mice.

Authors:  Gbola Olayiwola; Otas Ukponmwan; Dayo Olawode
Journal:  Afr J Tradit Complement Altern Med       Date:  2013-10-03

2.  Anticonvulsant and muscle relaxant activity of the ethanolic extract of stems of Dendrophthoe falcata (Linn. F.) in mice.

Authors:  Pooja Sinoriya; R Irchhaiya; Bhawna Sharma; Gayatri Sahu; Santosh Kumar
Journal:  Indian J Pharmacol       Date:  2011-11       Impact factor: 1.200

Review 3.  The role of flavonoids on oxidative stress in epilepsy.

Authors:  Tâmara Coimbra Diniz; Juliane Cabral Silva; Sarah Raquel Gomes de Lima-Saraiva; Fernanda Pires Rodrigues de Almeida Ribeiro; Alessandra Gomes Marques Pacheco; Rivelilson Mendes de Freitas; Lucindo José Quintans-Júnior; Jullyana de Souza Siqueira Quintans; Rosemairy Luciane Mendes; Jackson Roberto Guedes da Silva Almeida
Journal:  Oxid Med Cell Longev       Date:  2015-01-11       Impact factor: 6.543

4.  DNA barcoding of medicinal orchids in Asia.

Authors:  Bhakta Bahadur Raskoti; Rita Ale
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

5.  Antinociceptive, anti-inflammatory and acute toxicity effects of juglans regia L. Leaves in mice.

Authors:  H Hosseinzadeh; H Zarei; E Taghiabadi
Journal:  Iran Red Crescent Med J       Date:  2011-01-01       Impact factor: 0.611

6.  Screening of Methanol Extract and Ethyl Acetate Fraction of Abies webbiana Lindl. for Neuropharmacological Activities.

Authors:  O Parkash; D Kumar; S Kumar
Journal:  Indian J Pharm Sci       Date:  2015 Sep-Oct       Impact factor: 0.975
  6 in total

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