Literature DB >> 12164219

Synthesis, characterization of novel coupling products and 4-arylhydrazono-2-pyrazoline-5-ones as potential antimycobacterial agents.

S Güniz Küçükgüzel1, Sevim Rollas.   

Abstract

Novel coupling products 7a-d and 4-arylhydrazono-2-pyrazoline-5-ones 8a-e were synthesized and evaluated for antimycobacterial activity against Mycobacterium tuberculosis H37Rv and Mycobacterium avium. Compound 7b was found to be the most potent derivatives of the 7a-d series by an MIC value of 6.25 microg/ml.

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Year:  2002        PMID： 12164219     DOI： 10.1016/s0014-827x(02)01253-3

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  5 in total

1.  Synthesis, characterization and antimicrobial activity of certain novel aryl hydrazone pyrazoline-5-ones containing thiazole moiety.

Authors:  Maliki Reddy Dastagiri Reddy; Aluru Raghavendra Guru Prasad; Yadati Narasimha Spoorthy; Lakshmana Rao Krishna Rao Ravindranath
Journal:  Adv Pharm Bull       Date:  2013-02-07

Review 2.  Biological activities of hydrazone derivatives.

Authors:  Sevim Rollas; S Güniz Küçükgüzel
Journal:  Molecules       Date:  2007-08-17       Impact factor: 4.411

3.  Synthesis, in-vitro antimicrobial and antitubercular screening of Schiff bases of 3-amino-1-phenyl-4- [2-(4-phenyl-1,3-thiazol-2-yl) hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-one.

Authors:  K K Sivakumar; A Rajasekaran
Journal:  J Pharm Bioallied Sci       Date:  2013-04

4.  (E)-1-Benzyl-idene-2,2-diphenyl-hydrazine.

Authors:  Angel Mendoza; Ruth Meléndrez-Luevano; Blanca M Cabrera-Vivas; Claudia D Lozano-Márquez; Vladimir Carranza
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-01-18

5.  Synthesis, SAR Study and Evaluation of Mannich and Schiff Bases of Pyrazol-5(4H)-one Moiety Containing 3-(Hydrazinyl)-2-phenylquinazolin-4(3H)-one.

Authors:  K K Sivakumar; A Rajasekharan; R Rao; B Narasimhan
Journal:  Indian J Pharm Sci       Date:  2013-07       Impact factor: 0.975
  5 in total

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