Literature DB >> 12163618

The vaccinia virus I7L gene product is the core protein proteinase.

Chelsea M Byrd1, Tove' C Bolken, Dennis E Hruby.   

Abstract

Maturation of vaccinia virus (VV) core proteins is required for the production of infectious virions. The VV G1L and I7L gene products are the leading candidates for the viral core protein proteinase (vCPP). Using transient-expression assays, data were obtained to demonstrate that the I7L gene product and its encoded cysteine proteinase activity are responsible for vCPP activity.

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Year:  2002        PMID： 12163618      PMCID： PMC136993          DOI： 10.1128/jvi.76.17.8973-8976.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

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2.  An unusual active site identified in a family of zinc metalloendopeptidases.

Authors:  A B Becker; R A Roth
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

3.  Characterization of ts 16, a temperature-sensitive mutant of vaccinia virus.

Authors:  M Ericsson; S Cudmore; S Shuman; R C Condit; G Griffiths; J K Locker
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4.  Analysis of the role of the amino-terminal peptide of vaccinia virus structural protein precursors during proteolytic processing.

Authors:  P Lee; D E Hruby
Journal:  Virology       Date:  1995-02-20       Impact factor: 3.616

5.  Proteolytic cleavage of vaccinia virus virion proteins. Mutational analysis of the specificity determinants.

Authors:  P Lee; D E Hruby
Journal:  J Biol Chem       Date:  1994-03-18       Impact factor: 5.157

6.  trans processing of vaccinia virus core proteins.

Authors:  P Lee; D E Hruby
Journal:  J Virol       Date:  1993-07       Impact factor: 5.103

7.  Physical and molecular genetic analysis of the multistep proteolytic maturation pathway utilized by vaccinia virus P4a protein.

Authors:  S S Whitehead; N A Bersani; D E Hruby
Journal:  J Gen Virol       Date:  1995-03       Impact factor: 3.891

8.  A transcriptionally controlled trans-processing assay: putative identification of a vaccinia virus-encoded proteinase which cleaves precursor protein P25K.

Authors:  S S Whitehead; D E Hruby
Journal:  J Virol       Date:  1994-11       Impact factor: 5.103

9.  Proteolytic maturation of vaccinia virus core proteins: identification of a conserved motif at the N termini of the 4b and 25K virion proteins.

Authors:  J K VanSlyke; C A Franke; D E Hruby
Journal:  J Gen Virol       Date:  1991-02       Impact factor: 3.891

Review 10.  The role of proteolytic processing in the morphogenesis of virus particles.

Authors:  C U Hellen; E Wimmer
Journal:  Experientia       Date:  1992-02-15
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  41 in total

1.  Molecular dissection of the vaccinia virus I7L core protein proteinase.

Authors:  Chelsea M Byrd; Tove' C Bolken; Dennis E Hruby
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

2.  Polyprotein processing protease of African swine fever virus: purification and biochemical characterization.

Authors:  Daniel Rubio; Alí Alejo; Irene Rodríguez; María L Salas
Journal:  J Virol       Date:  2003-04       Impact factor: 5.103

3.  Investigation of structural and functional motifs within the vaccinia virus A14 phosphoprotein, an essential component of the virion membrane.

Authors:  Jason Mercer; Paula Traktman
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

4.  Role of the I7 protein in proteolytic processing of vaccinia virus membrane and core components.

Authors:  Camilo Ansarah-Sobrinho; Bernard Moss
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

5.  Cell biological and functional characterization of the vaccinia virus F10 kinase: implications for the mechanism of virion morphogenesis.

Authors:  Almira Punjabi; Paula Traktman
Journal:  J Virol       Date:  2005-02       Impact factor: 5.103

6.  Entry of vaccinia virus and cell-cell fusion require a highly conserved cysteine-rich membrane protein encoded by the A16L gene.

Authors:  Suany Ojeda; Tatiana G Senkevich; Bernard Moss
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

7.  Activity, specificity, and probe design for the smallpox virus protease K7L.

Authors:  Alexander E Aleshin; Marcin Drag; Naran Gombosuren; Ge Wei; Jowita Mikolajczyk; Arnold C Satterthwait; Alex Y Strongin; Robert C Liddington; Guy S Salvesen
Journal:  J Biol Chem       Date:  2012-09-25       Impact factor: 5.157

8.  Assembly and disassembly of the capsid-like external scaffold of immature virions during vaccinia virus morphogenesis.

Authors:  Himani Bisht; Andrea S Weisberg; Patricia Szajner; Bernard Moss
Journal:  J Virol       Date:  2009-07-01       Impact factor: 5.103

9.  The vaccinia virus F13L YPPL motif is required for efficient release of extracellular enveloped virus.

Authors:  Kady M Honeychurch; Guang Yang; Robert Jordan; Dennis E Hruby
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

10.  The vaccinia virus G1L putative metalloproteinase is essential for viral replication in vivo.

Authors:  Marika Hedengren-Olcott; Chelsea M Byrd; Jeffrey Watson; Dennis E Hruby
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103
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