| Literature DB >> 12163065 |
Joaquim Mendes1, Raphael Guerois, Luis Serrano.
Abstract
The progress achieved by several groups in the field of computational protein design shows that successful design methods include two major features: efficient algorithms to deal with the combinatorial exploration of sequence space and optimal energy functions to rank sequences according to their fitness for the given fold.Mesh:
Substances:
Year: 2002 PMID: 12163065 DOI: 10.1016/s0959-440x(02)00345-7
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN: 0959-440X Impact factor: 6.809