| Literature DB >> 12161153 |
Haripada Khatuya1, Richard H Hutchings, Gee-Hong Kuo, Virginia L Pulito, Linda K Jolliffe, Xiaobing Li, William V Murray.
Abstract
Antagonists of the alpha(1)-adrenergic receptors (alpha(1)-ARs) are useful for the treatment of benign prostatic hyperplasia. A series of potent and subtype-selective alpha(1a)-AR antagonists has been synthesized, displaying in vitro binding affinity in the low the nanomolar range.Entities:
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Year: 2002 PMID： 12161153 DOI： 10.1016/s0960-894x(02)00436-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823