| Literature DB >> 12161115 |
Chandan Singh1, Naveen Chandra Srivastav, Sunil K Puri.
Abstract
Building on the lead from antimalarial isonitriles 1-4 of marine origin, several easily accessible synthetic isonitriles were assessed for their antimalarial activity against Plasmodium falciparum (in vitro) and multidrug resistant Plasmodium yoelii in Swiss mice model (in vivo). Isonitrile 11 has shown promising activity in both these assays.Entities:
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Year: 2002 PMID： 12161115 DOI： 10.1016/s0960-894x(02)00457-2
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823