Literature DB >> 12153229

First total synthesis of natural 6-epiplakortolide e.

Mankil Jung1, Jungyeob Ham, Jueun Song.   

Abstract

[reaction: see text] Natural 6-epiplakortolide E was first synthesized from readily available 1-bromo-10-phenyldecane in 10 steps by using singlet oxygen-mediated Diels-Alder reaction to form cyclic peroxide followed by a directed iodolactonization to give the peroxylactone core.

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Year:  2002        PMID: 12153229     DOI: 10.1021/ol026285x

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Asymmetric Synthesis of 1,2-dioxanes: Approaches to the Peroxyplakoric Acids.

Authors:  Chunping Xu; Chris Schwartz; Joseph Raible; Patrick H Dussault
Journal:  Tetrahedron       Date:  2009-11-21       Impact factor: 2.457

Review 2.  Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products.

Authors:  Alexander O Terent'ev; Dmitry A Borisov; Vera A Vil'; Valery M Dembitsky
Journal:  Beilstein J Org Chem       Date:  2014-01-08       Impact factor: 2.883

Review 3.  Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions.

Authors:  Vera A Vil'; Ivan A Yaremenko; Alexey I Ilovaisky; Alexander O Terent'ev
Journal:  Molecules       Date:  2017-11-02       Impact factor: 4.411

  3 in total

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