Literature DB >> 12153137

A novel human hydroxysteroid dehydrogenase like 1 gene (HSDL1) is highly expressed in reproductive tissues.

Y Huang1, R Tang, J Dai, S Gu, W Zhao, C Cheng, M Xu, Z Zhou, K Ying, Y Xi, Y Mao.   

Abstract

We report the cloning and characterization of a novel human hydroxysteroid dehydrogenase like gene (HSDL1) located on human chromosome 16q24.2. The HSDL1 cDNA is 3407 base pair in length, encoding a 309 amino acid polypeptide related to human 17beta-HSD3. Northern blot reveals that the HSDL1 is highly expressed in testis and ovary. In situ hybridization indicates that the expression of HSDL1 is predominantly increased in the prostate cancer tissue compared with the normal prostate tissue, which suggests that the gene expression is important to the arising of prostate cancer.

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Year:  2001        PMID： 12153137     DOI： 10.1023/a:1015726217890

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  12 in total

Review 1.  17-beta-hydroxysteroid dehydrogenase in human breast and endometrial carcinoma. A new development in intracrinology.

Authors:  H Sasano; T Suzuki; J Takeyama; H Utsunomiya; K Ito; N Ariga; T Moriya
Journal:  Oncology       Date:  2000       Impact factor: 2.935

Review 2.  Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action.

Authors:  M E Baker
Journal:  Mol Cell Endocrinol       Date:  2001-01-22       Impact factor: 4.102

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Journal:  J Clin Endocrinol Metab       Date:  1999-12       Impact factor: 5.958

Review 4.  A guide to 17beta-hydroxysteroid dehydrogenases.

Authors:  J Adamski; F J Jakob
Journal:  Mol Cell Endocrinol       Date:  2001-01-22       Impact factor: 4.102

Review 5.  Structure and function of 17beta-hydroxysteroid dehydrogenase type 1 and type 2.

Authors:  P Vihko; V Isomaa; D Ghosh
Journal:  Mol Cell Endocrinol       Date:  2001-01-22       Impact factor: 4.102

6.  Structure and function of steroid dehydrogenases involved in hypertension, fertility, and cancer.

Authors:  W L Duax; D Ghosh
Journal:  Steroids       Date:  1997-01       Impact factor: 2.668

7.  Cloning and bacterial expression of monomeric short-chain dehydrogenase/reductase (carbonyl reductase) from CHO-K1 cells.

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Journal:  Eur J Biochem       Date:  2000-12

Review 8.  Crucial role of cytokines in sex steroid formation in normal and tumoral tissues.

Authors:  J Simard; S Gingras
Journal:  Mol Cell Endocrinol       Date:  2001-01-22       Impact factor: 4.102

9.  Deficient 17beta-hydroxysteroid dehydrogenase type 2 expression in endometriosis: failure to metabolize 17beta-estradiol.

Authors:  K Zeitoun; K Takayama; H Sasano; T Suzuki; N Moghrabi; S Andersson; A Johns; L Meng; M Putman; B Carr; S E Bulun
Journal:  J Clin Endocrinol Metab       Date:  1998-12       Impact factor: 5.958

Review 10.  Short-chain dehydrogenases/reductases (SDR).

Authors:  H Jörnvall; B Persson; M Krook; S Atrian; R Gonzàlez-Duarte; J Jeffery; D Ghosh
Journal:  Biochemistry       Date:  1995-05-09       Impact factor: 3.162
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  8 in total

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Journal:  Cancer Res       Date:  2022-04-15       Impact factor: 13.312

2.  Synthesis of saporin-antibody conjugates for targeting EpCAM positive tumour cells.

Authors:  Prasanna Kumar Athyala; Srujana Chitipothu; Jagat Rakesh Kanwar; Subramanian Krishnakumar; Janakiraman Narayanan
Journal:  IET Nanobiotechnol       Date:  2019-02       Impact factor: 1.847

3.  The distal end of porcine chromosome 6p is involved in the regulation of skatole levels in boars.

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Journal:  BMC Genet       Date:  2011-04-20       Impact factor: 2.797

4.  Evolution of retinoid and steroid signaling: vertebrate diversification from an amphioxus perspective.

Authors:  Ricard Albalat; Frédéric Brunet; Vincent Laudet; Michael Schubert
Journal:  Genome Biol Evol       Date:  2011-08-18       Impact factor: 3.416

5.  Genome Wide Association Study Identifies L3MBTL4 as a Novel Susceptibility Gene for Hypertension.

Authors:  Xin Liu; Cheng Hu; Minghui Bao; Jing Li; Xiaoyan Liu; Xuerui Tan; Yong Zhou; Yequn Chen; Shouling Wu; Shuohua Chen; Rong Zhang; Feng Jiang; Weiping Jia; Xingyu Wang; Xinchun Yang; Jun Cai
Journal:  Sci Rep       Date:  2016-08-02       Impact factor: 4.379

6.  Gene expression in reproductive organs of tsetse females - initial data in an approach to reduce fecundity.

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Journal:  BMC Microbiol       Date:  2018-11-23       Impact factor: 3.605

7.  Identification of candidate genes from androgenic gland in Macrobrachium nipponense regulated by eyestalk ablation.

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Journal:  Sci Rep       Date:  2021-10-06       Impact factor: 4.379

8.  Beta-Hydroxysteroid Dehydrogenase Genes in Orange-Spotted Grouper (Epinephelus coioides): Genome-Wide Identification and Expression Analysis During Sex Reversal.

Authors:  Ling Xiao; Yin Guo; Dengdong Wang; Mi Zhao; Xin Hou; Shuisheng Li; Haoran Lin; Yong Zhang
Journal:  Front Genet       Date:  2020-03-04       Impact factor: 4.599
  8 in total

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