Literature DB >> 12151894

Autologous osteochondral grafting in the knee: indication, results, and reflections.

Roland P Jakob1, Torsten Franz, Emmanuel Gautier, Pierre Mainil-Varlet.   

Abstract

The use of multiple autologous osteochondral plugs (mosaicplasty) for repair of articular cartilage defects is a well-accepted technique. Since 1995, the authors have used mosaicplasty to treat more than 110 patients with cartilage defects of the knee, hip, and ankle. The first 52 consecutive patients who had mosaicplasty of the knee and have an average followup of 37 months (range, 24-56 months) were examined. Indications for surgical treatment were osteochondritis dissecans, acute trauma, and posttraumatic lesions of the femorotibial joint, femoropatellar maltracking with recurrent episodes of patella dislocations, and distinct femoropatellar arthrosis. Preoperatively, cartilage defects were classified as International Cartilage Repair Society Grade III lesions in 23 patients and Grade IV lesions in 29 patients. Two years after surgery, an increased level of knee function was found in 86% of the patients. At the latest followup, improved knee function was observed in 92% of the patients. In four patients, reoperation was necessary because of graft failure. Complications and reoperation rate were related to large surface lesions. Autologous osteochondral transplantation is a valid option for the treatment of full-thickness osteochondral defects. However, the method is limited by the defect size and the number of plugs to be taken at the donor site.

Entities:  

Mesh:

Year:  2002        PMID: 12151894     DOI: 10.1097/00003086-200208000-00020

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  64 in total

1.  Prosthetic inlay resurfacing for the treatment of focal, full thickness cartilage defects of the femoral condyle: a bridge between biologics and conventional arthroplasty.

Authors:  Peter Bollars; Marc Bosquet; Bruno Vandekerckhove; François Hardeman; Johan Bellemans
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-11       Impact factor: 4.342

Review 2.  Surgical treatment for early osteoarthritis. Part I: cartilage repair procedures.

Authors:  A H Gomoll; G Filardo; L de Girolamo; J Espregueira-Mendes; J Esprequeira-Mendes; M Marcacci; W G Rodkey; J R Steadman; R J Steadman; S Zaffagnini; E Kon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-24       Impact factor: 4.342

3.  Surgical technique: Second-generation bone marrow stimulation via surgical dislocation to treat hip cartilage lesions.

Authors:  Michael Leunig; Lisa M Tibor; Florian D Naal; Reinhold Ganz; Matthias R Steinwachs
Journal:  Clin Orthop Relat Res       Date:  2012-12       Impact factor: 4.176

Review 4.  Osteochondritis Dissecans: Etiology, Pathology, and Imaging with a Special Focus on the Knee Joint.

Authors:  Juergen Bruns; Mathias Werner; Christian Habermann
Journal:  Cartilage       Date:  2017-06-22       Impact factor: 4.634

5.  Rehabilitation following osteochondral injury to the knee.

Authors:  Timothy F Tyler; Jennifer Y Lung
Journal:  Curr Rev Musculoskelet Med       Date:  2012-01-28

6.  Osteochondral autografts.

Authors:  Shantanu Patil; Sachin R Tapasvi
Journal:  Curr Rev Musculoskelet Med       Date:  2015-12

7.  Three-dimensional in vitro effects of compression and time in culture on aggregate modulus and on gene expression and protein content of collagen type II in murine chondrocytes.

Authors:  Kumar Chokalingam; Shawn Hunter; Cynthia Gooch; Chris Frede; Jane Florer; Richard Wenstrup; David Butler
Journal:  Tissue Eng Part A       Date:  2009-10       Impact factor: 3.845

8.  [Surgical treatment of knee joint osteoarthritis in the middle-aged patient].

Authors:  Martin Pietsch; Siegfried Hofmann
Journal:  Wien Med Wochenschr       Date:  2007-01

Review 9.  [Pain management in non-juvenile, aseptic osteonecrosis].

Authors:  M Jäger; A Werner; S Lentrodt; U Mödder; R Krauspe
Journal:  Schmerz       Date:  2004-12       Impact factor: 1.107

10.  Bone scintigraphy after osteochondral autograft transplantation in the knee: 13 patients followed for 4 years.

Authors:  Niels B Kock; Esther van Tankeren; Wim J G Oyen; Ate B Wymenga; Job L C van Susante
Journal:  Acta Orthop       Date:  2010-04-06       Impact factor: 3.717

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