Literature DB >> 12151572

Ulcerative colitis after statin treatment.

W E Rea1, D C S Durrant, D A R Boldy.   

Abstract

Statin treatment is widely used in both primary and secondary prevention of diseases in which hyperlipidaemia is a major risk factor, for example, ischaemic heart disease. The development of ulcerative colitis as an adverse reaction to simvastatin is reported, which, despite withdrawal of the drug, proved fatal. The adverse reaction profile of the statins is reviewed, which suggests that this is a class effect and not one limited to simvastatin.

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Year:  2002        PMID: 12151572      PMCID: PMC1742344          DOI: 10.1136/pmj.78.919.286

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  8 in total

1.  Microscopic colitis and Medication Use.

Authors:  Monina F Pascua; Prashant Kedia; Mark G Weiner; John Holmes; Jonas Ellenberg; James D Lewis
Journal:  Clin Med Insights Gastroenterol       Date:  2010-05-18

Review 2.  [Concomitant cardiovascular conditions in intestinal illness].

Authors:  P Rellecke; B E Strauer
Journal:  Internist (Berl)       Date:  2007-03       Impact factor: 0.743

3.  Statins and the Risk of Inflammatory Bowel Disease.

Authors:  Cong Dai; Min Jiang; Ming-Jun Sun
Journal:  Am J Gastroenterol       Date:  2016-12       Impact factor: 10.864

4.  Atorvastatin attenuates TNBS-induced rat colitis: the involvement of the TLR4/NF-kB signaling pathway.

Authors:  Amir Rashidian; Ahad Muhammadnejad; Ahmad-Reza Dehpour; Shahram Ejtemai Mehr; Maziar Mohammad Akhavan; Reza Shirkoohi; Mohsen Chamanara; Seyyedeh-Elaheh Mousavi; Seyed-Mahdi Rezayat
Journal:  Inflammopharmacology       Date:  2016-04-02       Impact factor: 4.473

5.  Simvastatin attenuates trinitrobenzene sulfonic acid-induced colitis, but not oxazalone-induced colitis.

Authors:  Maho Ikeda; Fuminao Takeshima; Hajime Isomoto; Saburo Shikuwa; Yohei Mizuta; Yoshiyuki Ozono; Shigeru Kohno
Journal:  Dig Dis Sci       Date:  2007-12-01       Impact factor: 3.199

Review 6.  Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism.

Authors:  Beatrice A Golomb; Marcella A Evans
Journal:  Am J Cardiovasc Drugs       Date:  2008       Impact factor: 3.571

7.  Randomized clinical trial: atorvastatin versus placebo in patients with acute exacerbation of mild to moderate ulcerative colitis.

Authors:  Puneet Dhamija; Debasish Hota; Rakesh Kochhar; Atul Sachdev; Amitava Chakrabarti
Journal:  Indian J Gastroenterol       Date:  2013-11-13

8.  Differential Effects of Statins on Inflammatory Interleukin-8 and Antimicrobial Peptide Human Β-Defensin 2 Responses in Salmonella-Infected Intestinal Epithelial Cells.

Authors:  Fu-Chen Huang; Shun-Chen Huang
Journal:  Int J Mol Sci       Date:  2018-06-02       Impact factor: 5.923

  8 in total

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