Literature DB >> 12150341

Thyrotoxicosis due to metastatic papillary thyroid cancer in a patient with Graves' disease.

S Basaria1, R Salvatori.   

Abstract

Thyrotoxicosis resulting from functional thyroid cancer metastases is extremely rare, and is mostly caused by follicular cancer. The lesions causing thyrotoxicosis are usually bulky and extensive. We report here a patient with Graves' disease and concomitant papillary thyroid cancer who developed metastases causing symptomatic thyrotoxicosis. His serum titers of thyroid stimulating Ig (TSIs) were elevated. We believe that TSIs were responsible for thyrotoxicosis by stimulating hormonogenesis in the metastatic lesions.

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Year:  2002        PMID： 12150341     DOI： 10.1007/BF03345090

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN： 0391-4097            Impact factor:   4.256


  21 in total

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Journal:  J Endocrinol Invest       Date:  1990-04       Impact factor: 4.256
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  3 in total

1.  A rare cause of hyperthyroidism: functioning thyroid metastases.

Authors:  Daphne Gardner; Su Chin Ho
Journal:  BMJ Case Rep       Date:  2014-10-09

2.  An Unusual Case of Metastatic Functional Thyroid Carcinoma With a Remarkable Treatment Response to Radioactive Iodine.

Authors:  Ari Geliebter; Erika F Brutsaert; Martin I Surks
Journal:  J Endocr Soc       Date:  2017-08-08

3.  Hyperfunctioning thyroid carcinoma: A systematic review.

Authors:  Jun Liu; Ye Wang; Dongzhu Da; Miao Zheng
Journal:  Mol Clin Oncol       Date:  2019-10-01
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