Literature DB >> 12150066

[Immunity of children aged 6-8 against pertussis, tetanus and diphtheria].

Janusz Slusarczyk1, Grazyna Dulny, Krystyna Nowak, Jolanta Krszyna, Teresa Wysokińska, Anna Fordymacka, Anna Gzyl, Wiesława Janaszek, Grzegorz Gniadek.   

Abstract

Vaccination against pertussis has been performed since 1960. Whole cell pertussis vaccine produced by Plant of Sera and Vaccines Biomed S.A. in Kraków, has been used. After vaccination has been introduced, epidemiological situation of pertussis in Poland improved, but in 90's the decrease of immunity was observed. The aim of this work was to determine pertussis immunity of children after several years from the last dose of pertussis vaccine. For comparison purposes immunity against tetanus and diphtheria was tested. Protective antibody levels were detected in 70%, 58%, and 45% children aged 6, 7, and 8, respectively. It shows that decrease of immunity may cause increasing number of pertussis in children above 5. Taking into consideration our results, it seems necessary to introduce additional dose of pertussis vaccine among children aged 5 years. The level of tetanus and diphtheria antibodies was high in all tested groups.

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Year:  2002        PMID: 12150066

Source DB:  PubMed          Journal:  Przegl Epidemiol        ISSN: 0033-2100


  2 in total

1.  Strain variation among Bordetella pertussis isolates circulating in Poland after 50 years of whole-cell pertussis vaccine use.

Authors:  Ewa Mosiej; Ewa Augustynowicz; Monika Zawadka; Waldemar Dabrowski; Anna Lutyńska
Journal:  J Clin Microbiol       Date:  2011-02-09       Impact factor: 5.948

2.  Clinical presentation of pertussis in fully immunized children in Lithuania.

Authors:  Irena Narkeviciute; Ema Kavaliunaite; Genovaite Bernatoniene; Rimantas Eidukevicius
Journal:  BMC Infect Dis       Date:  2005-05-27       Impact factor: 3.090

  2 in total

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