Literature DB >> 12148988

Oxidative induction of beta-turn conformations in cyclic peptidomimetics: conformational analyses as indicators of configuration.

Luyong Jiang1, Kevin Burgess.   

Abstract

Solid-phase syntheses of the cyclic peptidomimetics 1-4 were performed. Sulfide 1 and sulfoxide 3 did not tend to exist in beta-turn conformations in solution, but the sulfone 2 and the epimeric sulfoxide 4 did. The assignment of configuration of the sulfoxides is based on the conformational analyses.

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Year:  2002        PMID： 12148988     DOI： 10.1021/ja0171411

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  3 in total

1.  Structure-activity relationship studies of gonadotropin-releasing hormone antagonists containing S-aryl/alkyl norcysteines and their oxidized derivatives.

Authors:  Manoj P Samant; Richard White; Doley J Hong; Glenn Croston; P Michael Conn; Jo Ann Janovick; Jean Rivier
Journal:  J Med Chem       Date:  2007-04-03       Impact factor: 7.446

2.  Synthesis of thiophenylalanine-containing peptides via Cu(I)-mediated cross-coupling.

Authors:  Christina R Forbes; Neal J Zondlo
Journal:  Org Lett       Date:  2012-01-06       Impact factor: 6.005

3.  Synthesis of cyclic peptides through direct aminolysis of peptide thioesters catalyzed by imidazole in aqueous organic solutions.

Authors:  Yangmei Li; Austin Yongye; Marc Giulianotti; Karina Martinez-Mayorga; Yongping Yu; Richard A Houghten
Journal:  J Comb Chem       Date:  2009 Nov-Dec
  3 in total

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