Literature DB >> 12147838

Testicular microlithiasis: prospective analysis of prevalence and associated tumor.

William D Middleton1, Sharlene A Teefey, Cynthia S Santillan.   

Abstract

PURPOSE: To evaluate testicular microlithiasis (TM) prospectively with modern state-of-the-art equipment.
MATERIALS AND METHODS: Information concerning indication for examination, presence and degree of TM, presence of testicular tumor, and patient age was prospectively recorded for all patients referred for scrotal ultrasonography between 1996 and 1999. High-frequency linear transducers (7.5 MHz or higher) were used. TM was divided into classic (CTM) and limited (LTM) on the basis of the presence of five or more microliths on one or more images of the testes. Fisher exact tests were used for determining significant differences in proportions.
RESULTS: Data in 1,079 patients were analyzed. The overall prevalence of TM was 18.1% (195 of 1,079). Forty (3.7%) patients had CTM, and 155 (14.4%) had LTM; 15 (1.4%) had tumors visible at US. Tumors were present in three (8%) of 40 patients with CTM (seminoma in two, embryonal cell in one), nine (5.8%) of 155 with LTM (seminoma in six, mixed germ cell in one, Leydig cell in two), and three (0.3%) of 884 with no TM (seminoma in two, other in one). There was no difference between CTM and LTM (P =.72) in the rate of coexisting tumor. There was a significant difference between no TM and CTM or LTM (P </=.001) in the rate of coexisting tumor. Eighty percent (12 of 15) of patients with tumor at presentation had CTM or LTM.
CONCLUSION: Approximately one of 27 patients had CTM, and one of seven had LTM. Although a majority of patients with testicular tumors had coexistent TM, more than 90% with TM (both CTM and LTM) did not have tumor at presentation. Copyright RSNA, 2002

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Mesh:

Year:  2002        PMID: 12147838     DOI: 10.1148/radiol.2242011137

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  24 in total

1.  Testicular microlithiasis: another starry sky appearance.

Authors:  Adedayo A Onitilo
Journal:  Clin Med Res       Date:  2007-10

Review 2.  Pediatric scrotal ultrasound: review and update.

Authors:  Noor A Alkhori; Richard A Barth
Journal:  Pediatr Radiol       Date:  2017-08-04

3.  Testicular Microlithiasis: Patient Compliance in a Two-Year Follow-Up Program.

Authors:  M R Pedersen; P J S Osther; F B Soerensen; S R Rafaelsen
Journal:  Ultrasound Int Open       Date:  2016-08-24

4.  Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis.

Authors:  Ayse Corut; Abdurrahman Senyigit; Sibel Aylin Ugur; Sedat Altin; Ugur Ozcelik; Haluk Calisir; Zeki Yildirim; Ayhan Gocmen; Aslihan Tolun
Journal:  Am J Hum Genet       Date:  2006-08-29       Impact factor: 11.025

5.  Testicular microlithiasis an ultrasound dilemma: survey of opinions regarding significance and management amongst UK ultrasound practitioners.

Authors:  D Shetty; A G Bailey; S J Freeman
Journal:  Br J Radiol       Date:  2013-12-05       Impact factor: 3.039

6.  Evaluation of testicular tumour calcification with digital orchiography.

Authors:  Umit Aksoy Ozcan; Yeşim Sağlıcan; Mehmet Erdem Yıldız; Yeşim Yıldırım; Hakan Ozveri; Firuze Ocak; Ercan Karaarslan
Journal:  Eur Radiol       Date:  2013-06-08       Impact factor: 5.315

7.  Testicular microlithiasis: is there a need for surveillance in the absence of other risk factors?

Authors:  Jonathan Richenberg; Nick Brejt
Journal:  Eur Radiol       Date:  2012-06-19       Impact factor: 5.315

8.  Severe hypokinesis caused by paraneoplastic anti-Ma2 encephalitis associated with bilateral intratubular germ-cell neoplasm of the testes.

Authors:  Lumine Matsumoto; Tomotaka Yamamoto; Mana Higashihara; Izumi Sugimoto; Hisatomo Kowa; Junji Shibahara; Koichiro Nakamura; Jun Shimizu; Yoshikazu Ugawa; Jun Goto; Josep Dalmau; Shoji Tsuji
Journal:  Mov Disord       Date:  2007-04-15       Impact factor: 10.338

9.  Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients.

Authors:  Fiona N A C Miller; Shantini Rosairo; Jane L Clarke; Seshadri Sriprasad; Gordon H Muir; Paul S Sidhu
Journal:  Eur Radiol       Date:  2006-05-18       Impact factor: 5.315

Review 10.  Magnetic resonance imaging and ultrasound evaluation of penile and testicular masses.

Authors:  E Andipa; K Liberopoulos; C Asvestis
Journal:  World J Urol       Date:  2004-08-06       Impact factor: 4.226

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