BACKGROUND: Connective tissue disorders, such as some forms of Ehlers-Danlos syndrome, have been associated with severe periodontitis. METHODS: This report describes a case of Marfan's syndrome, an inherited disorder of connective tissue caused by mutations in the fibrillin-1 gene, in which the patient presented with severe periodontitis. RESULTS: At examination, an average full-mouth clinical attachment level loss of 5.6+/-2.1 mm, furcation involvement, and severe alveolar bone loss were observed in a 41-year-old Caucasian male. Tooth hypermobility was also present. CONCLUSIONS: This case appears to be the first documentation of severe periodontitis in a patient with Marfan's syndrome. It supports the hypothesis that a variety of connective tissue disorders may confer increased susceptibility to periodontal tissue breakdown.
BACKGROUND: Connective tissue disorders, such as some forms of Ehlers-Danlos syndrome, have been associated with severe periodontitis. METHODS: This report describes a case of Marfan's syndrome, an inherited disorder of connective tissue caused by mutations in the fibrillin-1 gene, in which the patient presented with severe periodontitis. RESULTS: At examination, an average full-mouth clinical attachment level loss of 5.6+/-2.1 mm, furcation involvement, and severe alveolar bone loss were observed in a 41-year-old Caucasian male. Tooth hypermobility was also present. CONCLUSIONS: This case appears to be the first documentation of severe periodontitis in a patient with Marfan's syndrome. It supports the hypothesis that a variety of connective tissue disorders may confer increased susceptibility to periodontal tissue breakdown.
Authors: Mohammad Khursheed Alam; Ahmed Ali Alfawzan; Deepti Shrivastava; Kumar Chandan Srivastava; Haytham Jamil Alswairki; Samir Mussallam; Huda Abutayyem; Naseer Ahmed Journal: Int J Environ Res Public Health Date: 2022-04-21 Impact factor: 4.614
Authors: Ingmar Staufenbiel; Christian Hauschild; Bärbel Kahl-Nieke; Eva Vahle-Hinz; Yskert von Kodolitsch; Maike Berner; Oskar Bauss; Werner Geurtsen; Alexander Rahman Journal: BMC Oral Health Date: 2013-10-28 Impact factor: 2.757