Literature DB >> 12145191

N-glycosylation profile of recombinant human soluble Fcgamma receptor III.

Noriko Takahashi1, Joel Cohen-Solal, Annie Galinha, Wolf Herman Fridman, Catherine Sautès-Fridman, Koichi Kato.   

Abstract

N-glycans of human Fcgamma receptor III (FcgammaR III) are believed to be involved in the interaction with complement receptor type 3 (CR3) (Sehgal et al. [1993] J. Immunol., 150, 4571-4580). Recombinant human soluble FcgammaRIII (rhsFcgammaRIII), which is produced in baby hamster kidney (BHK) cells, has been shown to interact with CR3 in a manner similar to native FcgammaRIII. We elucidated the N-glycosylation profiles of rhsFcgammaRIII by the 3D high-performance liquid chromatography mapping technique. It was revealed that the N-glycans of rhsFcgammaRIII are much more divergent (consisting of 20 neutral, 7 monosialyl, 4 disialyl, 5 trisialyl, and 1 tetrasialyl oligosaccharides) than those previously determined for BHK-expressed mouse sFcgammaRII, notwithstanding close structural similarity of polypeptide chains between the two sFcgammaRs. Particularly, high-mannose type oligosaccharides are specifically expressed on rhsFcgammaRIII.

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Year:  2002        PMID： 12145191     DOI： 10.1093/glycob/cwf063

Source DB:  PubMed          Journal:  Glycobiology        ISSN： 0959-6658            Impact factor:   4.313


  10 in total

1.  CD16a with oligomannose-type N-glycans is the only "low-affinity" Fc γ receptor that binds the IgG crystallizable fragment with high affinity in vitro.

Authors:  Ganesh P Subedi; Adam W Barb
Journal:  J Biol Chem       Date:  2018-09-13       Impact factor: 5.157

2.  Impact of N-glycosylation on Fcγ receptor / IgG interactions: unravelling differences with an enhanced surface plasmon resonance biosensor assay based on coiled-coil interactions.

Authors:  Florian Cambay; Olivier Henry; Yves Durocher; Gregory De Crescenzo
Journal:  MAbs       Date:  2019-03-05       Impact factor: 5.857

3.  Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab.

Authors:  Jerrard M Hayes; Asa Frostell; Robert Karlsson; Steffen Müller; Silvia Míllan Martín; Martin Pauers; Franziska Reuss; Eoin F Cosgrave; Cecilia Anneren; Gavin P Davey; Pauline M Rudd
Journal:  Mol Cell Proteomics       Date:  2017-06-02       Impact factor: 5.911

4.  Restricted processing of CD16a/Fc γ receptor IIIa N-glycans from primary human NK cells impacts structure and function.

Authors:  Kashyap R Patel; Jacob T Roberts; Ganesh P Subedi; Adam W Barb
Journal:  J Biol Chem       Date:  2018-01-12       Impact factor: 5.157

5.  Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans.

Authors:  Tsunehiro Mizushima; Hirokazu Yagi; Emi Takemoto; Mami Shibata-Koyama; Yuya Isoda; Shigeru Iida; Kazuhiro Masuda; Mitsuo Satoh; Koichi Kato
Journal:  Genes Cells       Date:  2011-11       Impact factor: 1.891

Review 6.  Fc gamma receptors: glycobiology and therapeutic prospects.

Authors:  Jerrard M Hayes; Mark R Wormald; Pauline M Rudd; Gavin P Davey
Journal:  J Inflamm Res       Date:  2016-11-16

7.  Site-specific N-glycosylation analysis of soluble Fcγ receptor IIIb in human serum.

Authors:  Hirokazu Yagi; Daisuke Takakura; Lubka T Roumenina; Wolf Herman Fridman; Catherine Sautès-Fridman; Nana Kawasaki; Koichi Kato
Journal:  Sci Rep       Date:  2018-02-09       Impact factor: 4.379

Review 8.  Multiple Variables at the Leukocyte Cell Surface Impact Fc γ Receptor-Dependent Mechanisms.

Authors:  Kashyap R Patel; Jacob T Roberts; Adam W Barb
Journal:  Front Immunol       Date:  2019-02-14       Impact factor: 7.561

9.  Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation.

Authors:  Nathaniel Washburn; Robin Meccariello; Jay Duffner; Kristen Getchell; Kimberly Holte; Thomas Prod'homme; Karunya Srinivasan; Robert Prenovitz; Jonathan Lansing; Ishan Capila; Ganesh Kaundinya; Anthony M Manning; Carlos J Bosques
Journal:  Mol Cell Proteomics       Date:  2018-12-17       Impact factor: 5.911

10.  Role of N-Glycosylation in FcγRIIIa interaction with IgG.

Authors:  Julie Van Coillie; Morten A Schulz; Arthur E H Bentlage; Noortje de Haan; Zilu Ye; Dionne M Geerdes; Wim J E van Esch; Lise Hafkenscheid; Rebecca L Miller; Yoshiki Narimatsu; Sergey Y Vakhrushev; Zhang Yang; Gestur Vidarsson; Henrik Clausen
Journal:  Front Immunol       Date:  2022-09-09       Impact factor: 8.786
  10 in total

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