| Literature DB >> 12142374 |
Abstract
Tumor-associated trypsin inhibitor (TATI) is a low-molecular-weight (6 kDa) trypsin inhibitor that has been used as a marker for ovarian cancer. It is also expressed together with tumor-associated trypsin by many other tumors, and increased serum concentrations of TATI occur in connection with these. TATI is a prognostic marker for ovarian, bladder, and kidney cancer, which may be associated with the participation of trypsin in protease cascades contributing to tumor invasiveness.Entities:
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Year: 2002 PMID: 12142374
Source DB: PubMed Journal: Clin Chem ISSN: 0009-9147 Impact factor: 8.327