Literature DB >> 12140207

Remodelling the filtration bleb.

J E Morgan1, J P Diamond, S D Cook.   

Abstract

AIMS: To report remodelling of enlarged dysmorphic filtration blebs with conjunctival compression sutures and autologous blood injection.
METHODS: A retrospective analysis of consecutively recruited patients with enlarged and dysmorphic filtration blebs who were managed with conjunctival compression sutures and subconjunctival autologous blood injections. Under topical anaesthesia, conjunctival (8.0-9.0 Nylon or 8.0 Vicryl) compression sutures were placed either side of blebs that were not showing signs of spontaneous resolution. In each case up to 0.75 ml of autologous blood was then injected into the areas of the bleb to be flattened. Supplemental injections of autologous blood were given in clinic as required.
RESULTS: In 11 eyes of 11 patients, conjunctival compression sutures were placed and autologous blood was injected, on average, 568 days following filtration surgery (range 41-2023). Supplemental autologous blood injections were required in eight patients, with three injections being given in one patient. In each case, the sutures were well tolerated and satisfactory compression of the conjunctiva was achieved. The highest intraocular pressure following injection was 25 mm Hg (mean 17.3, SD 4.2) and in none of the cases did blood enter the anterior chamber or parts of the filtration bleb bounded by the sutures.
CONCLUSION: Conjunctival compression sutures with autologous blood provide a simple and effective means for remodelling the filtration bleb. The procedure can be performed under topical anaesthesia and does not hinder further bleb surgery, should this be required.

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Year:  2002        PMID: 12140207      PMCID: PMC1771237          DOI: 10.1136/bjo.86.8.872

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  15 in total

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2.  Results of intraoperative 5-fluorouracil supplementation on trabeculectomy for open-angle glaucoma.

Authors:  M F Smith; M B Sherwood; J W Doyle; P T Khaw
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3.  Donor scleral graft patching for persistent filtration bleb leak.

Authors:  S Melamed; I Ashkenazi; D C Belcher; M Blumenthal
Journal:  Ophthalmic Surg       Date:  1991-03

4.  Closure of fornix-based posttrabeculectomy conjunctival wound leaks with autologous fibrin glue.

Authors:  S L Graham; B Murray; I Goldberg
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5.  A serious complication of intrableb injection of autologous blood for the treatment of postfiltration hypotony.

Authors:  M M Zaltas; J S Schuman
Journal:  Am J Ophthalmol       Date:  1994-08-15       Impact factor: 5.258

6.  The complications of trabeculectomy (a 20-year follow-up).

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7.  Glaucoma filtering bleb dysesthesia.

Authors:  D L Budenz; K Hoffman; A Zacchei
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8.  Loss of visual acuity after trabeculectomy.

Authors:  V P Costa; M Smith; G L Spaeth; S Gandham; B Markovitz
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9.  Reconstruction of filtering blebs with free conjunctival autografts.

Authors:  J N Buxton; K T Lavery; J M Liebmann; D F Buxton; R Ritch
Journal:  Ophthalmology       Date:  1994-04       Impact factor: 12.079

10.  Hypotony and choroidal detachment as late complications of trabeculectomy.

Authors:  E N Burney; H A Quigley; A L Robin
Journal:  Am J Ophthalmol       Date:  1987-05-15       Impact factor: 5.258

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2.  Flap suture--a simple technique for the revision of hypotony maculopathy following trabeculectomy with mitomycin C.

Authors:  Judith Eha; Esther M Hoffmann; Jochen Wahl; Norbert Pfeiffer
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4.  Efficacy and safety of transconjunctival scleral flap resuturing for hypotony after glaucoma filtering surgery.

Authors:  Katsuhiko Maruyama; Shiroaki Shirato
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-08-28       Impact factor: 3.117

5.  Lens Extraction for Management of Coexisting Cataract and Post-filtering Surgery Ocular Hypotony.

Authors:  Ghasem Fakhraie; Zahra Mohajernezhad-Fard; Sasan Moghimi; Zakieh Vahedian; Yadollah Eslami; Reza Zarei
Journal:  J Ophthalmic Vis Res       Date:  2015 Oct-Dec

6.  Hypotony Management through Transconjunctival Scleral Flap Resuturing: Analysis of Surgical Outcomes and Success Predictors.

Authors:  Ana Luiza B Scoralick; Izabela Almeida; Michele Ushida; Diego T Dias; Syril Dorairaj; Tiago S Prata; Fábio N Kanadani
Journal:  J Curr Glaucoma Pract       Date:  2017-08-05

7.  Long-term outcomes of blebs repaired with scleral patch graft and conjunctival advancement in late-onset leak post-trabeculectomy.

Authors:  Vanita Pathak Ray; Swathi V Badakere
Journal:  Indian J Ophthalmol       Date:  2021-09       Impact factor: 1.848

8.  Commentary: Long term outcomes of blebs repaired with scleral patch graft and conjunctival advancement in late-onset leak post-trabeculectomy.

Authors:  Manju R Pillai
Journal:  Indian J Ophthalmol       Date:  2021-09       Impact factor: 1.848

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