OBJECTIVES: To study post-exercise facilitation following a non-fatigue exercise in a homogenous group of multiple sclerosis (MS) patients with complaints of muscle fatigue. METHODS: In 15 MS patients and matched controls motor evoked potentials (MEP) were recorded from the biceps brachii muscle at time delays of 0.5-30s after an isometric contraction with a torque of 50% of maximal voluntary contraction (MVC) maintained for 2-6s. In addition, MEP was recorded after isometric torque of 25, 50, and 100% of MVC maintained for 6s. RESULTS: Isometric non-fatigue contraction induced significant post-exercise increase in MEP amplitude in MS patients compared with controls being most pronounced after a contraction for 6s. The post-exercise increase in MEP lasted for longer than 30s in MS patients. CONCLUSIONS: Post-exercise increase of MEP amplitude following a non-fatigue exercise was significant in MS patients with complaints of muscle fatigue compared with healthy subjects.
OBJECTIVES: To study post-exercise facilitation following a non-fatigue exercise in a homogenous group of multiple sclerosis (MS) patients with complaints of muscle fatigue. METHODS: In 15 MSpatients and matched controls motor evoked potentials (MEP) were recorded from the biceps brachii muscle at time delays of 0.5-30s after an isometric contraction with a torque of 50% of maximal voluntary contraction (MVC) maintained for 2-6s. In addition, MEP was recorded after isometric torque of 25, 50, and 100% of MVC maintained for 6s. RESULTS: Isometric non-fatigue contraction induced significant post-exercise increase in MEP amplitude in MSpatients compared with controls being most pronounced after a contraction for 6s. The post-exercise increase in MEP lasted for longer than 30s in MSpatients. CONCLUSIONS: Post-exercise increase of MEP amplitude following a non-fatigue exercise was significant in MSpatients with complaints of muscle fatigue compared with healthy subjects.
Authors: Gary W Thickbroom; Paul Sacco; Allan G Kermode; Sarah A Archer; Michelle L Byrnes; Andrew Guilfoyle; Frank L Mastaglia Journal: J Neurol Date: 2006-04-10 Impact factor: 4.849
Authors: Franca Tecchio; Andrea Cancelli; Carlo Cottone; Giancarlo Zito; Patrizio Pasqualetti; Anna Ghazaryan; Paolo Maria Rossini; Maria Maddalena Filippi Journal: J Neurol Date: 2014-05-23 Impact factor: 4.849
Authors: Franca Tecchio; A Cancelli; C Cottone; L Tomasevic; B Devigus; G Zito; Matilde Ercolani; F Carducci Journal: Front Hum Neurosci Date: 2013-04-22 Impact factor: 3.169