Literature DB >> 12139984

The hair cell's transduction channel.

Meredith Strassmaier1, Peter G Gillespie.   

Abstract

The elusive transduction channel is the key player in mechanical transduction by the sensory hair cells of the inner ear. Multiple factors have thwarted molecular identification of this channel, including the lack of a definitive pharmacological signature, the paucity of hair cells, and the uniqueness of their transduction mechanism. At present, we are forced to speculate as to the transduction channel's identity; functional characteristics suggest, however, that it may well belong to transient receptor potential superfamily of ion channels.

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Year:  2002        PMID: 12139984     DOI: 10.1016/s0959-4388(02)00344-6

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  12 in total

1.  Varitint-waddler: a double whammy for hearing.

Authors:  Karen P Steel
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-04       Impact factor: 11.205

Review 2.  Molecular conservation and novelties in vertebrate ear development.

Authors:  B Fritzsch; K W Beisel
Journal:  Curr Top Dev Biol       Date:  2003       Impact factor: 4.897

Review 3.  Keeping sensory cells and evolving neurons to connect them to the brain: molecular conservation and novelties in vertebrate ear development.

Authors:  B Fritzsch; K W Beisel
Journal:  Brain Behav Evol       Date:  2004       Impact factor: 1.808

4.  Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells.

Authors:  Jung-Bum Shin; Dany Adams; Martin Paukert; Maria Siba; Samuel Sidi; Michael Levin; Peter G Gillespie; Stefan Gründer
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-22       Impact factor: 11.205

5.  Mechanosensitive currents in the neurites of cultured mouse sensory neurones.

Authors:  Jing Hu; Gary R Lewin
Journal:  J Physiol       Date:  2006-10-12       Impact factor: 5.182

6.  Effects of intracellular pH and Ca2+ on the activity of stretch-sensitive cation channels in leech neurons.

Authors:  C Barsanti; M Pellegrini; D Ricci; M Pellegrino
Journal:  Pflugers Arch       Date:  2006-04-04       Impact factor: 3.657

7.  Two interdependent TRPV channel subunits, inactive and Nanchung, mediate hearing in Drosophila.

Authors:  Zhefeng Gong; Wonseok Son; Yun Doo Chung; Janghwan Kim; Dong Wook Shin; Colleen A McClung; Yong Lee; Hye Won Lee; Deok-Jin Chang; Bong-Kiun Kaang; Hawon Cho; Uhtaek Oh; Jay Hirsh; Maurice J Kernan; Changsoo Kim
Journal:  J Neurosci       Date:  2004-10-13       Impact factor: 6.167

8.  Hair-cell versus afferent adaptation in the semicircular canals.

Authors:  R D Rabbitt; R Boyle; G R Holstein; S M Highstein
Journal:  J Neurophysiol       Date:  2004-08-11       Impact factor: 2.714

9.  Avian magnetite-based magnetoreception: a physiologist's perspective.

Authors:  Hervé Cadiou; Peter A McNaughton
Journal:  J R Soc Interface       Date:  2010-01-27       Impact factor: 4.118

10.  Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing.

Authors:  Carolina Roza; Jean-Luc Puel; Michaela Kress; Anne Baron; Sylvie Diochot; Michel Lazdunski; Rainer Waldmann
Journal:  J Physiol       Date:  2004-05-28       Impact factor: 5.182

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