Literature DB >> 12139430

A fatal case of necrotizing sinusitis due to toxigenic Corynebacterium ulcerans.

Nele Wellinghausen1, Andreas Sing, Winfried V Kern, Sven Perner, Reinhard Marre, Jochen Rentschler.   

Abstract

A 77-year-old farmer developed cough with sputum production, fever, bloody nasal discharge and a mass in his right maxillary sinus leading to necrotic ulceration of the sinus. Corynebacterium ulcerans, carrying the beta-phage for the diphtheria toxin and secreting the toxin, was detected microscopically and by culture from the sinusoidal and ulcer discharge. Despite immediate antimicrobial chemotherapy the patient died of pulmonary failure associated with the production of large amounts of very viscous sputum. Identification of the causative agent, pathophysiological aspects and risk factors of this unusal infection are discussed.

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Year:  2002        PMID: 12139430     DOI: 10.1078/1438-4221-00186

Source DB:  PubMed          Journal:  Int J Med Microbiol        ISSN: 1438-4221            Impact factor:   3.473


  10 in total

1.  Analysis of toxigenic Corynebacterium ulcerans strains revealing potential for false-negative real-time PCR results.

Authors:  Pamela K Cassiday; Lucia C Pawloski; Tejpratap Tiwari; Gary N Sanden; Patricia P Wilkins
Journal:  J Clin Microbiol       Date:  2007-11-07       Impact factor: 5.948

2.  Detection of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by a novel real-time PCR.

Authors:  Regina Schuhegger; Marion Lindermayer; Rudolf Kugler; Jürgen Heesemann; Ulrich Busch; Andreas Sing
Journal:  J Clin Microbiol       Date:  2008-06-11       Impact factor: 5.948

3.  Human clinical isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans collected in Canada from 1999 to 2003 but not fitting reporting criteria for cases of diphtheria.

Authors:  Leanne M Dewinter; Kathryn A Bernard; Marc G Romney
Journal:  J Clin Microbiol       Date:  2005-07       Impact factor: 5.948

4.  Characterization of toxigenic Corynebacterium ulcerans strains isolated from humans and domestic cats in the United Kingdom.

Authors:  Aruni De Zoysa; Peter M Hawkey; Kathy Engler; Robert George; Gina Mann; William Reilly; David Taylor; Androulla Efstratiou
Journal:  J Clin Microbiol       Date:  2005-09       Impact factor: 5.948

5.  Rapid detection and molecular differentiation of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by LightCycler PCR.

Authors:  Andreas Sing; Anja Berger; Wulf Schneider-Brachert; Thomas Holzmann; Udo Reischl
Journal:  J Clin Microbiol       Date:  2011-05-18       Impact factor: 5.948

6.  Corynebacterium ulcerans in an immunocompromised patient with diphtheria and her dog.

Authors:  Marie-Frédérique Lartigue; Xavier Monnet; Anne Le Flèche; Patrick A D Grimont; Jean-Jacques Benet; Antoine Durrbach; Monique Fabre; Patrice Nordmann
Journal:  J Clin Microbiol       Date:  2005-02       Impact factor: 5.948

7.  Unwanted baggage.

Authors:  Nicolas Leitz; Zarqa Leitz; Martin Schaller
Journal:  BMJ Case Rep       Date:  2013-05-08

8.  Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.

Authors:  Andreas Sing; Michael Hogardt; Suse Bierschenk; Jürgen Heesemann
Journal:  J Clin Microbiol       Date:  2003-10       Impact factor: 5.948

9.  A case report and epidemiological investigation of axillary lymph node abscess caused by Corynebacterium ulcerans in an HIV-1-positive patient.

Authors:  Y Yoshimura; N Tachikawa; T Komiya; A Yamamoto
Journal:  Epidemiol Infect       Date:  2013-09-20       Impact factor: 4.434

Review 10.  Coagulase-negative staphylococci (CoNS) as a significant etiological factor of laryngological infections: a review.

Authors:  Michał Michalik; Alfred Samet; Adrianna Podbielska-Kubera; Vincenzo Savini; Jacek Międzobrodzki; Maja Kosecka-Strojek
Journal:  Ann Clin Microbiol Antimicrob       Date:  2020-06-04       Impact factor: 3.944

  10 in total

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