Literature DB >> 12139016

Cyclipostins: novel hormone-sensitive lipase inhibitors from Streptomyces sp. DSM 13381. I. Taxonomic studies of the producer microorganism and fermentation results.

J Wink1, F R Schmidt, G Seibert, W Aretz.   

Abstract

The cyclipostins are a group of hormone-sensitive lipase inhibitors produced by a Streptomyces species. Having verticillate spore chains this strain exhibits significant differences to the known species of the former genus Streptoverticillium. Taxonomic studies and fermentation results are presented.

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Year:  2002        PMID： 12139016     DOI： 10.7164/antibiotics.55.472

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  2 in total

1.  The first total synthesis of (±)-cyclophostin and (±)-cyclipostin P: inhibitors of the serine hydrolases acetyl cholinesterase and hormone sensitive lipase.

Authors:  Raj K Malla; Saibal Bandyopadhyay; Christopher D Spilling; Supratik Dutta; Cynthia M Dupureur
Journal:  Org Lett       Date:  2011-05-17       Impact factor: 6.005

2.  Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin.

Authors:  Saibal Bandyopadhyay; Supratik Dutta; Christopher D Spilling; Cynthia M Dupureur; Nigam P Rath
Journal:  J Org Chem       Date:  2008-09-27       Impact factor: 4.354
  2 in total

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