Literature DB >> 12137994

Oxidative decontamination of chemical and biological warfare agents using L-Gel.

Ellen Raber1, Raymond McGuire.   

Abstract

A decontamination method has been developed using a single reagent that is effective both against chemical warfare (CW) and biological warfare (BW) agents. The new reagent, "L-Gel", consists of an aqueous solution of a mild commercial oxidizer, Oxone, together with a commercial fumed silica gelling agent, Cab-O-Sil EH-5. L-Gel is non-toxic, environmentally friendly, relatively non-corrosive, maximizes contact time because of its thixotropic nature, clings to walls and ceilings, and does not harm carpets or painted surfaces. The new reagent also addresses the most demanding requirements for decontamination in the civilian sector, including availability, low maintenance, ease of application and deployment by a variety of dispersal mechanisms, minimal training and acceptable expense. Experiments to test the effectiveness of L-Gel were conducted at Lawrence Livermore National Laboratory and independently at four other locations. L-Gel was tested against all classes of chemical warfare agents and against various biological warfare agent surrogates, including spore-forming bacteria and non-virulent strains of real biological agents. Testing showed that L-Gel is as effective against chemical agents and biological materials, including spores, as the best military decontaminants.

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Year:  2002        PMID: 12137994     DOI: 10.1016/s0304-3894(02)00051-1

Source DB:  PubMed          Journal:  J Hazard Mater        ISSN: 0304-3894            Impact factor:   10.588


  7 in total

1.  Decontamination options for Bacillus anthracis-contaminated drinking water determined from spore surrogate studies.

Authors:  Ellen Raber; Alison Burklund
Journal:  Appl Environ Microbiol       Date:  2010-08-13       Impact factor: 4.792

Review 2.  Review of Decontamination Techniques for the Inactivation of Bacillus anthracis and Other Spore-Forming Bacteria Associated with Building or Outdoor Materials.

Authors:  Joseph P Wood; Alden Charles Adrion
Journal:  Environ Sci Technol       Date:  2019-04-02       Impact factor: 9.028

3.  Decontamination of Bacillus anthracis Spores at Subzero Temperatures by Complete Submersion.

Authors:  Chad Laing; Timothy Janzen; Vladimir Blinov; Konstantin Volchek; Noriko Goji; Matthew Thomas; Melissa Telfer; Elizabeth Rohonczy; Kingsley K Amoako
Journal:  Appl Biosaf       Date:  2021-03-19

4.  Development of quantitative real-time PCR assays for detection and quantification of surrogate biological warfare agents in building debris and leachate.

Authors:  Pascal E Saikaly; Morton A Barlaz; Francis L de Los Reyes
Journal:  Appl Environ Microbiol       Date:  2007-08-24       Impact factor: 4.792

5.  Chemical warfare agents.

Authors:  K Ganesan; S K Raza; R Vijayaraghavan
Journal:  J Pharm Bioallied Sci       Date:  2010-07

6.  Design and construction of a low cost air purifier for killing harmful airborne microorganisms using a combination of a strong multi-directional electric-field and an ultra violet light.

Authors:  D N P Ruwan Jayakantha; H M N Bandara; Nadeesha M Gunawardana; R P V Jayantha Rajapakse; Dulari S Thilakarathne; Elisabetta Comini; Nanda Gunawardhana; S M M L Karunarathne
Journal:  HardwareX       Date:  2022-02-11

Review 7.  Respiratory protection against bioaerosols: literature review and research needs.

Authors:  Appavoo Rengasamy; Ziqing Zhuang; Roland Berryann
Journal:  Am J Infect Control       Date:  2004-10       Impact factor: 2.918

  7 in total

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