Literature DB >> 1213675

Some new bifunctional reagents for the conjugation of a protein with an amino compound in water.

G I Tesser, R A de Hoog-Declerck, L W Westerhuis.   

Abstract

Five symmetrical bifunctional reagents (I-V) have been synthesized and tested for their usefulness for the conjugation of albumin with tryptophan, in aqueous solution. With I and II about 17, with IV and V about 8 tryptophan residues could be introduced in the native protein. The difference is discussed. Reagent III has a very low solubility in water but may be useful if organic solvents are permissible.

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Year:  1975        PMID: 1213675     DOI: 10.1515/bchm2.1975.356.2.1625

Source DB:  PubMed          Journal:  Hoppe Seylers Z Physiol Chem        ISSN: 0018-4888


  3 in total

1.  Adipokinetic hormone and AKH-like peptide demonstrated in the corpora cardiaca and nervous system of Locusta migratoria by immunocytochemistry.

Authors:  H Schooneveld; G I Tesser; J A Veenstra; H M Romberg-Privee
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249

2.  Analysis of near-neighbor contacts in bacteriophage T4 wedges and hubless baseplates by using a cleavable chemical cross-linker.

Authors:  N R Watts; D H Coombs
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

3.  Traceless Cleavage of Protein-Biotin Conjugates under Biologically Compatible Conditions.

Authors:  Joseph Cowell; Matthew Buck; Ali H Essa; Rebecca Clarke; Waldemar Vollmer; Daniela Vollmer; Catharien M Hilkens; John D Isaacs; Michael J Hall; Joe Gray
Journal:  Chembiochem       Date:  2017-07-19       Impact factor: 3.164

  3 in total

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