Mitochondria and Apoptosis.

Apoptosis is an important biological process it plays critical role in cell growth differentiation as well as the response toward outside stimulus. Recently it was found that the mitochondrial transmembrane potential and mitochondrial permeability transition have a remarkable role in the process of apoptosis. Hypothesis of a permeability transition pore complex located in the mitochondrial membranes was postulated and had got extensive interest. This subject was introduced in the present minireview.