Literature DB >> 12134048

Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism.

Armin Papkalla1, Jan Münch, Claas Otto, Frank Kirchhoff.   

Abstract

We investigated the infectivities and replicative capacities of a large panel of variants of the molecular human immunodeficiency virus type 1 (HIV-1) NL4-3 clone that differ exclusively in the V3 region of the viral envelope glycoprotein and the nef gene. Our results demonstrate that Nef enhances virion infectivity and HIV-1 replication independently of the viral coreceptor tropism.

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Year:  2002        PMID： 12134048      PMCID： PMC155138          DOI： 10.1128/jvi.76.16.8455-8459.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  46 in total

1.  Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A.

Authors:  C Aiken
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

2.  A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation.

Authors:  L Alexander; Z Du; M Rosenzweig; J U Jung; R C Desrosiers
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

3.  Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling.

Authors:  A J Iafrate; S Bronson; J Skowronski
Journal:  EMBO J       Date:  1997-02-17       Impact factor: 11.598

4.  Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys.

Authors:  Z Du; S M Lang; V G Sasseville; A A Lackner; P O Ilyinskii; M D Daniel; J U Jung; R C Desrosiers
Journal:  Cell       Date:  1995-08-25       Impact factor: 41.582

5.  Infectivity enhancement by HIV-1 Nef is dependent on the pathway of virus entry: implications for HIV-based gene transfer systems.

Authors:  T Luo; J L Douglas; R L Livingston; J V Garcia
Journal:  Virology       Date:  1998-02-15       Impact factor: 3.616

6.  Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein.

Authors:  M W Pandori; N J Fitch; H M Craig; D D Richman; C A Spina; J C Guatelli
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

7.  Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease.

Authors:  A A Bukovsky; T Dorfman; A Weimann; H G Göttlinger
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

8.  Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis.

Authors:  C Aiken; D Trono
Journal:  J Virol       Date:  1995-08       Impact factor: 5.103

9.  Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase.

Authors:  R Welker; H Kottler; H R Kalbitzer; H G Kräusslich
Journal:  Virology       Date:  1996-05-01       Impact factor: 3.616

10.  Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients.

Authors:  N J Deacon; A Tsykin; A Solomon; K Smith; M Ludford-Menting; D J Hooker; D A McPhee; A L Greenway; A Ellett; C Chatfield; V A Lawson; S Crowe; A Maerz; S Sonza; J Learmont; J S Sullivan; A Cunningham; D Dwyer; D Dowton; J Mills
Journal:  Science       Date:  1995-11-10       Impact factor: 47.728
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  54 in total

1.  Recent Insights into HIV Accessory Proteins.

Authors:  Jenny L. Anderson; Thomas J. Hope
Journal:  Curr Infect Dis Rep       Date:  2003-10       Impact factor: 3.725

2.  Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection.

Authors:  Franziska Arnold; Jacqueline Schnell; Onofrio Zirafi; Christina Stürzel; Christoph Meier; Tanja Weil; Ludger Ständker; Wolf-Georg Forssmann; Nadia R Roan; Warner C Greene; Frank Kirchhoff; Jan Münch
Journal:  J Virol       Date:  2011-11-16       Impact factor: 5.103

Review 3.  HIV accessory proteins and surviving the host cell.

Authors:  Jenny L Anderson; Thomas J Hope
Journal:  Curr HIV/AIDS Rep       Date:  2004-04       Impact factor: 5.071

4.  Macrophage internal HIV-1 is protected from neutralizing antibodies.

Authors:  Herwig Koppensteiner; Carina Banning; Carola Schneider; Heinrich Hohenberg; Michael Schindler
Journal:  J Virol       Date:  2011-12-28       Impact factor: 5.103

5.  Natural Inhibitor of Human Cytomegalovirus in Human Seminal Plasma.

Authors:  Sina Lippold; Berenike Braun; Franziska Krüger; Mirja Harms; Janis A Müller; Rüdiger Groß; Jan Münch; Jens von Einem
Journal:  J Virol       Date:  2019-03-05       Impact factor: 5.103

6.  HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

Authors:  Lara Manganaro; Elisa de Castro; Ana M Maestre; Kevin Olivieri; Adolfo García-Sastre; Ana Fernandez-Sesma; Viviana Simon
Journal:  J Virol       Date:  2015-07-15       Impact factor: 5.103

7.  Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.

Authors:  Stuart A Sievers; John Karanicolas; Howard W Chang; Anni Zhao; Lin Jiang; Onofrio Zirafi; Jason T Stevens; Jan Münch; David Baker; David Eisenberg
Journal:  Nature       Date:  2011-06-15       Impact factor: 49.962

8.  A naturally occurring variation in the proline-rich region does not attenuate human immunodeficiency virus type 1 nef function.

Authors:  Elke Rücker; Jan Münch; Steffen Wildum; Matthias Brenner; Jutta Eisemann; Leonid Margolis; Frank Kirchhoff
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

9.  A molecular tweezer antagonizes seminal amyloids and HIV infection.

Authors:  Edina Lump; Laura M Castellano; Christoph Meier; Janine Seeliger; Nelli Erwin; Benjamin Sperlich; Christina M Stürzel; Shariq Usmani; Rebecca M Hammond; Jens von Einem; Gisa Gerold; Florian Kreppel; Kenny Bravo-Rodriguez; Thomas Pietschmann; Veronica M Holmes; David Palesch; Onofrio Zirafi; Drew Weissman; Andrea Sowislok; Burkhard Wettig; Christian Heid; Frank Kirchhoff; Tanja Weil; Frank-Gerrit Klärner; Thomas Schrader; Gal Bitan; Elsa Sanchez-Garcia; Roland Winter; James Shorter; Jan Münch
Journal:  Elife       Date:  2015-08-18       Impact factor: 8.140

10.  Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue.

Authors:  Michael Schindler; Devi Rajan; Carina Banning; Peter Wimmer; Herwig Koppensteiner; Alicja Iwanski; Anke Specht; Daniel Sauter; Thomas Dobner; Frank Kirchhoff
Journal:  Retrovirology       Date:  2010-01-15       Impact factor: 4.602
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