Literature DB >> 12131320

Diagnostic steps in the evaluation of patients with erectile dysfunction.

Dimitrios Hatzichristou1, Konstantinos Hatzimouratidis, Michael Bekas, Apostolos Apostolidis, Vasilios Tzortzis, Konstantinos Yannakoyorgos.   

Abstract

PURPOSE: The necessity for a thorough diagnostic evaluation for erectile dysfunction has been questioned after the availability of effective oral therapies. We determined the impact of the different diagnostic steps on the management strategy for erectile dysfunction.
MATERIALS AND METHODS: The study included all patients who presented at an andrology outpatient clinic during a 4-year period. Baseline evaluation included medical and sexual history, blood tests, physical examination and intracavernous injection test. Patients with normal initial screening were evaluated with specific diagnostic procedures. The results were analyzed to identify the diagnostic potential of each screening step separately.
RESULTS: Overall 1,644 patients presented at the clinic during the study period, of whom 368 (22.4%) were excluded from study due to severe psychiatric (5.2%) or cardiovascular (2.7%) disease, or to a history of erectile dysfunction less than 3 months in duration (14.5%). In the remaining 1,276 patients with a mean age plus or minus standard deviation of 56 +/- 14 years, and a mean duration of erectile dysfunction of 4.9 +/- 3.4 years medical history revealed erectile dysfunction associated medical conditions in 57%, blood tests identified previously undiagnosed medical conditions in 6.2%, and physical examination and the intracavernous injection test were diagnostic in 13.9% and 2.6%, respectively. Initial screening was negative in 259 cases (20.3%), in which specific diagnostic procedures identified an underlying vascular pathology in 165 (12.9%) and unfavorable penile geometry in 16 (1.3%). The remaining 78 men (6.1%) had no evidence of organic disease.
CONCLUSIONS: Baseline diagnostic evaluation for erectile dysfunction can identify the underlying pathological condition or erectile dysfunction associated risk factors in 80% of patients. Such screening may diagnose reversible causes of erectile dysfunction and also unmask medical conditions that manifest with erectile dysfunction as the first symptom. Specific diagnostic procedures may be limited in patients with primary erectile dysfunction or those without risk factors. Such clinical data support previously published guidelines for erectile dysfunction management.

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Year:  2002        PMID: 12131320

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  11 in total

1.  [Diagnosis of erectile dysfunction--what is still needed today?].

Authors:  W-H Weiske
Journal:  Urologe A       Date:  2003-10       Impact factor: 0.639

2.  Current Diagnosis and Management of Erectile Dysfunction.

Authors:  Alexander W Pastuszak
Journal:  Curr Sex Health Rep       Date:  2014-09

3.  Clinical significance and expression of microRNA in diabetic patients with erectile dysfunction.

Authors:  X I Jiang; Yong Luo; Shuli Zhao; Qichao Chen; Chao Jiang; Yutian Dai; Yun Chen; Zhigang Cao
Journal:  Exp Ther Med       Date:  2015-04-22       Impact factor: 2.447

4.  Evaluation of arterial stiffness and cardiac function in patients with vascular erectile dysfunction: acute effects of phosphodiesterase-5 inhibitor tadalafil.

Authors:  O Özdabakoğlu; S Güllülü; S Sağ; T Şentürk; H Kiliçarslan; A Tütüncü; M Keçebaş; I Baran; A Aydinlar
Journal:  Int J Impot Res       Date:  2016-12-08       Impact factor: 2.896

Review 5.  Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction.

Authors:  Abdulmaged M Traish; Irwin Goldstein; Noel N Kim
Journal:  Eur Urol       Date:  2007-02-20       Impact factor: 20.096

Review 6.  A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient?

Authors:  Konstantinos Hatzimouratidis; Dimitrios G Hatzichristou
Journal:  Drugs       Date:  2005       Impact factor: 9.546

Review 7.  A Critical Analysis of Methodology Pitfalls in Duplex Doppler Ultrasound in the Evaluation of Patients With Erectile Dysfunction: Technical and Interpretation Deficiencies.

Authors:  Bruno Nascimento; Eduardo P Miranda; Jean-Etienne Terrier; Felipe Carneiro; John P Mulhall
Journal:  J Sex Med       Date:  2020-07-03       Impact factor: 3.937

8.  Comparison of the simplified International Index of Erectile Function (IIEF-5) in patients of erectile dysfunction with different pathophysiologies.

Authors:  Zhengyan Tang; Dongjie Li; Xiaobo Zhang; Lu Yi; Xiangsheng Zhu; Xiangyang Zeng; Yuxin Tang
Journal:  BMC Urol       Date:  2014-07-05       Impact factor: 2.264

Review 9.  Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence.

Authors:  Konstantinos Hatzimouratidis
Journal:  Clin Interv Aging       Date:  2006       Impact factor: 4.458

Review 10.  Korean Society for Sexual Medicine and Andrology (KSSMA) Guideline on Erectile Dysfunction.

Authors:  Ji Kan Ryu; Kang Su Cho; Su Jin Kim; Kyung Jin Oh; Sung Chul Kam; Kyung Keun Seo; Hong Seok Shin; Soo Woong Kim
Journal:  World J Mens Health       Date:  2013-08-31       Impact factor: 5.400

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