| Literature DB >> 12130866 |
Keiko Hojo1, Yuichi Susuki, Masahiko Sasaki, Mitsuko Maeda, Timothy John Smith, Koichi Kawasaki.
Abstract
An amino acid type poly(ethylene glycol) is a useful tool for preparation of a bi- or multivalent poly(ethylene glycol) hybrid of bioactive peptides, but synthesis is problematic. The amino acid type poly(ethylene glycol) was prepared from poly(oxyethylene)diglycolic acid followed by introduction of a fluorenylmethyloxycarbonyl group. The resulting product could be purified easily by LH-20 column chromatography and HPLC.Entities:
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Year: 2002 PMID： 12130866 DOI： 10.1248/cpb.50.1001
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645