Literature DB >> 12128260

Ultrastructural features and ICSI treatment of severe teratozoospermia: report of two human cases of globozoospermia.

Luciano G Nardo1, Fulvia Sinatra, Giovanni Bartoloni, Salvatore Zafarana, Filadelfo Nardo.   

Abstract

Abnormal sperm morphology is associated with male infertility. We describe two human cases of globozoospermia (round-headed spermatozoa) together with fine diagnosis and proposed treatment. Scanning and transmission electron microscopy (SEM and TEM) were performed to identify the ultrastructural features. Female partners underwent ovarian hyperstimulation and intracytoplasmic sperm injection (ICSI). Fertilized oocytes were transferred 36 h later. One couple had a healthy live-birth. Ultrastructural analysis may help to diagnose sperm morphology and identify those which will respond to treatment.

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Year:  2002        PMID: 12128260     DOI: 10.1016/s0301-2115(01)00602-9

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN: 0301-2115            Impact factor:   2.435


  4 in total

1.  Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancy.

Authors:  S L Taylor; S Y Yoon; M S Morshedi; D R Lacey; T Jellerette; R A Fissore; S Oehninger
Journal:  Reprod Biomed Online       Date:  2009-12-28       Impact factor: 3.828

2.  Proteome analysis of round-headed and normal spermatozoa by 2-D fluorescence difference gel electrophoresis and mass spectrometry.

Authors:  Ting-Ting Liao; Zhen Xiang; Wen-Bing Zhu; Li-Qing Fan
Journal:  Asian J Androl       Date:  2009-10-12       Impact factor: 3.285

Review 3.  The present status of artificial oocyte activation in assisted reproductive technology.

Authors:  Kaoru Yanagida; Yoko Fujikura; Haruo Katayose
Journal:  Reprod Med Biol       Date:  2008-08-03

4.  Sperm parameters, protamine deficiency, and apoptosis in total globozoospermia.

Authors:  Jalal Ghasemzadeh; Ali Reza Talebi; Mohammad Ali Khalili; Farzaneh Fesahat; Iman Halvaei; Ali Nabi; Sareh Ashourzadeh
Journal:  Iran J Reprod Med       Date:  2015-08
  4 in total

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