| Literature DB >> 12128090 |
Catherine A Rottkamp1, Craig S Atwood, James A Joseph, Akihiko Nunomura, George Perry, Mark A Smith.
Abstract
Investigators studying the primary culprit responsible for Alzheimer disease have, for the past two decades, primarily focused on amyloid-beta (Abeta). Here, we put Abeta on trial and review evidence amassed by the prosecution that implicate Abeta and also consider arguments and evidence gathered by the defense team who are convinced of the innocence of their client. As in all trials, the arguments provided by the prosecution and defense revolve around the same evidence, with opposing interpretations. Below, we present a brief synopsis of the trial for you, the jury, to decide the verdict. Amyloid-beta: guilty or not-guilty?Entities:
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Year: 2002 PMID： 12128090 DOI： 10.1016/s0196-9781(02)00069-4
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750