| Literature DB >> 12127759 |
David H Rowitch1, Q Richard Lu, Nicoletta Kessaris, William D Richardson.
Abstract
Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.Mesh:
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Year: 2002 PMID: 12127759 DOI: 10.1016/s0166-2236(02)02201-4
Source DB: PubMed Journal: Trends Neurosci ISSN: 0166-2236 Impact factor: 13.837