Literature DB >> 12127717

Encapsulation of pancreatic islets for transplantation in diabetes: the untouchable islets.

Paul de Vos1, Piero Marchetti.   

Abstract

The aim of encapsulation of pancreatic islets is to transplant in the absence of immunosuppression. It is based on the principle that transplanted tissue is protected from the host immune system by an artificial membrane. Encapsulation allows for application of insulin-secreting cells of animal or other surrogate sources, to overcome human islet shortage. The advantages and pitfalls of the approaches developed so far are discussed and compared, together with some recent progress, in view of applicability in clinical islet transplantation.

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Year:  2002        PMID： 12127717     DOI： 10.1016/s1471-4914(02)02381-x

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  27 in total

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5.  Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.

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Review 6.  Transplantable bioartificial pancreas devices: current status and future prospects.

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Journal:  Transplantation       Date:  2016-08       Impact factor: 4.939
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