Literature DB >> 12126401

New routes to N-alkylated cyclic sulfamidates.

Jeffrey J Posakony1, John R Grierson, Timothy J Tewson.   

Abstract

BOC- and dibenzosuberyl-protected chiral and hindered cyclic sulfamidates ([1,2,3]-oxathiazolidine-2,2-dioxides) were synthesized and subsequently deprotected using trifluoroacetic acid. The resulting crystalline sulfamidates were then used in several alkylation reactions involving benzyl bromide and alcohols in a versatile route to cyclic sulfamidates with differing N-alkyl substituents.

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Year:  2002        PMID： 12126401     DOI： 10.1021/jo0157019

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

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Authors:  Weiping Yu; Jonathan McConathy; Larry Williams; Vernon M Camp; Eugene J Malveaux; Zhaobin Zhang; Jeffrey J Olson; Mark M Goodman
Journal:  J Med Chem       Date:  2010-01-28       Impact factor: 7.446

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Authors:  Tetsuya Nishimura; Kazue Takahata; Yuri Kosugi; Takaaki Tanabe; Shizuko Muraoka
Journal:  J Neural Transm (Vienna)       Date:  2017-02-17       Impact factor: 3.575

3.  Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity.

Authors:  Laureano L Sabatier; Pablo H Palestro; Andrea V Enrique; Valentina Pastore; María L Sbaraglini; Pedro Martín; Luciana Gavernet
Journal:  J Enzyme Inhib Med Chem       Date:  2019-12       Impact factor: 5.051

Review 4.  Recent progress toward the asymmetric synthesis of carbon-substituted piperazine pharmacophores and oxidative related heterocycles.

Authors:  Plato A Magriotis
Journal:  RSC Med Chem       Date:  2020-05-22
  4 in total

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