Literature DB >> 12125978

Determination of the subcellular distribution of mercaptoundecahydro-closo-dodecaborate (BSH) in human glioblastoma multiforme by electron microscopy.

Michael Neumann1, Ulrike Kunz, Heiner Lehmann, Detlef Gabel.   

Abstract

The subcellular distribution of mercaptoundecahydro-closo-dodecaborate (BSH) in glioblastoma multiforme tissue sections of several patients having received BSH prior to surgery was investigated by transmission electron microscopy (TEM) using antibodies against BSH and electron energy loss spectroscopy (EELS) and electron spectroscopic imaging (ESI). These microscopic techniques show that BSH is associated with extracellular structures, the cell membrane as well as with the chromatin in the nucleus.

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Year:  2002        PMID： 12125978     DOI： 10.1023/a:1015737010621

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  17 in total

1.  cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

Authors:  D Z Fisher; N Chaudhary; G Blobel
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

2.  Analytical calculation of boron- 10 dosage in cell nucleus for neutron capture therapy.

Authors:  T Kobayashi; K Kanda
Journal:  Radiat Res       Date:  1982-07       Impact factor: 2.841

3.  Binding and distribution of Na2B12H11SH on cellular and subcellular level in tumor tissue of glioma patients in boron neutron capture therapy.

Authors:  B Otersen; D Haritz; F Grochulla; M Bergmann; W Sierralta; D Gabel
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

4.  Spectromicroscopy of boron in human glioblastomas following administration of Na2B12H11SH.

Authors:  B Gilbert; L Perfetti; O Fauchoux; J Redondo; P A Baudat; R Andres; M Neumann; S Steen; D Gabel; D Mercanti; M T Ciotti; P Perfetti; G Margaritondo; G De Stasio
Journal:  Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics       Date:  2000-07

5.  Clinical phase-I study of Na2B12H11SH (BSH) in patients with malignant glioma as precondition for boron neutron capture therapy (BNCT).

Authors:  D Haritz; D Gabel; R Huiskamp
Journal:  Int J Radiat Oncol Biol Phys       Date:  1994-03-30       Impact factor: 7.038

6.  Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.

Authors:  F Lin; H J Worman
Journal:  Genomics       Date:  1995-05-20       Impact factor: 5.736

7.  Human brain tumors: assessment with in vivo proton MR spectroscopy.

Authors:  D Ott; J Hennig; T Ernst
Journal:  Radiology       Date:  1993-03       Impact factor: 11.105

8.  Phagocytic capacity of normal and malignant rat glial cells in culture.

Authors:  R Bjerknes; R Bjerkvig; O D Laerum
Journal:  J Natl Cancer Inst       Date:  1987-02       Impact factor: 13.506

9.  In vitro posttranslational modification of lamin B cloned from a human T-cell line.

Authors:  K M Pollard; E K Chan; B J Grant; K F Sullivan; E M Tan; C A Glass
Journal:  Mol Cell Biol       Date:  1990-05       Impact factor: 4.272

10.  Performance of sulfhydryl boron hydride in patients with grade III and IV astrocytoma: a basis for boron neutron capture therapy.

Authors:  C P Ceberg; A Persson; A Brun; R Huiskamp; A S Fyhr; B R Persson; L G Salford
Journal:  J Neurosurg       Date:  1995-07       Impact factor: 5.115
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  2 in total

1.  Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model.

Authors:  Marcela A Garabalino; Elisa M Heber; Andrea Monti Hughes; Sara J González; Ana J Molinari; Emiliano C C Pozzi; Susana Nievas; Maria E Itoiz; Romina F Aromando; David W Nigg; William Bauer; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2013-04-17       Impact factor: 1.925

2.  Diagnostic significance of intraoperative ultrasound contrast in evaluating the resection degree of brain glioma by transmission electron microscopic examination.

Authors:  Shu-Qing Yu; Ji-Sheng Wang; Si-Yuan Chen; Xiang-Ming Liu; Yan Li; Yi-Ming Ding; Xiao-Ya Li; Yi-Lin Sun; Hui Chen
Journal:  Chin Med J (Engl)       Date:  2015-01-20       Impact factor: 2.628
  2 in total

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