Literature DB >> 12125250

[Use of the plant hepatoprotector Galstena tuberculostatics-induced hepatic lesions: experimental and clinical study].

O Iu Katikova, B M Asanov, M A Vize-Khripunova, E N Burba, V I Ruzov.   

Abstract

The efficiency of the use of the natural drug Galstena (Richard Bittner GmbH) was experimentally and clinically studied on a model of damage induced by toxic doses of tuberculostatics (rifampicin, isoniazid, pyrazinamide) in laboratory rats and in patients with different forms of pulmonary tuberculosis and with hepatitis caused by specific antituberculous drug therapy, who were treated at the Clinic of Phthiziology. Galstena was found to have marked hepatoprotective properties and to be able to prevent renal and pancreatic disorders. The drug also showed an antioxidative activity. The use of Galstena in patients with pulmonary tuberculosis substantially reduced the magnitude of clinical and laboratory signs of drug-induced hepatic damage.

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Year:  2002        PMID: 12125250

Source DB:  PubMed          Journal:  Probl Tuberk        ISSN: 0032-9533


  1 in total

Review 1.  Drugs and herbs given to prevent hepatotoxicity of tuberculosis therapy: systematic review of ingredients and evaluation studies.

Authors:  Qin Liu; Paul Garner; Yang Wang; Binghua Huang; Helen Smith
Journal:  BMC Public Health       Date:  2008-10-21       Impact factor: 3.295

  1 in total

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