Literature DB >> 12124647

Mechanisms of amnestic effect of ergot alkaloid agroclavin.

N V Bobkova1, V K Uteshev, N I Medvinskaya, I V Nesterova, M U Arinbasarov.   

Abstract

Neurochemical mechanisms of the effect of agroclavin on spatial memory in the Morris water maze in mice were studied by analyzing the effect of neurotransmitter receptor ligands on the amnestic effect of this alkaloid. D1-receptor agonist SKF-38393 and calcium channel blockers verapamil and nimodipine abolished the negative effect of agroclavin on spatial memory. The role of intracellular calcium in the mechanisms of amnestic effect of agroclavin is discussed.

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Year:  2002        PMID: 12124647     DOI: 10.1023/a:1016298005058

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Cooccurrence of mycotoxins in maize and poultry feeds from Brazil by liquid chromatography/tandem mass spectrometry.

Authors:  Maria de Lourdes Mendes de Souza; Michael Sulyok; Otniel Freitas-Silva; Sônia Soares Costa; Catherine Brabet; Miguel Machinski Junior; Beatriz Leiko Sekiyama; Eugenia Azevedo Vargas; Rudolf Krska; Rainer Schuhmacher
Journal:  ScientificWorldJournal       Date:  2013-11-14
  1 in total

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