Literature DB >> 12123724

Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.

David R Mole1, Christopher W Pugh, Peter J Ratcliffe, Patrick H Maxwell.   

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Year:  2002        PMID: 12123724     DOI: 10.1016/s0065-2571(01)00037-1

Source DB:  PubMed          Journal:  Adv Enzyme Regul        ISSN: 0065-2571


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  6 in total

1.  Anti-angiogenic Therapy for Retinal Disease.

Authors:  Yannis M Paulus; Akrit Sodhi
Journal:  Handb Exp Pharmacol       Date:  2017

2.  Hypoxia-inducible factor-1 facilitates cervical cancer progression in human papillomavirus type 16 transgenic mice.

Authors:  Zhi Hong Lu; Jason D Wright; Brian Belt; Robert D Cardiff; Jeffrey M Arbeit
Journal:  Am J Pathol       Date:  2007-06-28       Impact factor: 4.307

3.  A positive feedback loop promotes HIF-1α stability through miR-210-mediated suppression of RUNX3 in paraquat-induced EMT.

Authors:  Yong Zhu; Jinfeng Wang; Xiaoxiao Meng; Hui Xie; Jiuting Tan; Xinkun Guo; Peng Han; Ruilan Wang
Journal:  J Cell Mol Med       Date:  2017-07-12       Impact factor: 5.310

4.  USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.

Authors:  May Zaw Thin; Theodore Evan; Jessica K Nelson; Steven Howell; Mary Wu; Bruna Almeida; Nathalie Legrave; Duco S Koenis; Gabriela Koifman; Yoichiro Sugimoto; Miriam Llorian Sopena; James MacRae; Emma Nye; Michael Howell; Ambrosius P Snijders; Andreas Prachalias; Yoh Zen; Debashis Sarker; Axel Behrens
Journal:  Nat Commun       Date:  2022-04-19       Impact factor: 17.694

Review 5.  Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy.

Authors:  K G Pringle; K L Kind; A N Sferruzzi-Perri; J G Thompson; C T Roberts
Journal:  Hum Reprod Update       Date:  2009-11-19       Impact factor: 15.610

Review 6.  The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective.

Authors:  Parviz Mammadzada; Pablo M Corredoira; Helder André
Journal:  Cell Mol Life Sci       Date:  2019-12-31       Impact factor: 9.261

  6 in total

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