Literature DB >> 12123623

Molecular mechanisms of immunomodulatory activity of glucocorticoids.

Carlo Riccardi1, Stefano Bruscoli, Graziella Migliorati.   

Abstract

The development and function of cells in the immune system are regulated by many intrinsic and extrinsic factors. One class of molecule that affects immune cells belongs to the neuroendocrine system and the best-studied mediators in this category are glucocorticoids. These are small lypophilic molecules that participate in a wide number of normal and pathologic processes. This paper concentrates on their physiologic and pharmacologic effects on the immune response.

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Year:  2002        PMID： 12123623     DOI： 10.1006/phrs.2002.0969

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN： 1043-6618            Impact factor:   7.658


  26 in total

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3.  Glucocorticoid production and regulation in thymus: of mice and birds.

Authors:  Celso E Gomez-Sanchez
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4.  Corticosterone impairs dendritic cell maturation and function.

Authors:  Michael D Elftman; Christopher C Norbury; Robert H Bonneau; Mary E Truckenmiller
Journal:  Immunology       Date:  2007-10       Impact factor: 7.397

5.  Biomaterial adjuvant effect is attenuated by anti-inflammatory drug delivery or material selection.

Authors:  Lori W Norton; Jaehyung Park; Julia E Babensee
Journal:  J Control Release       Date:  2010-06-02       Impact factor: 9.776

6.  Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitis.

Authors:  Yi Zhu; Fang Xie; Liang Ding; Xiaoyu Fan; Xinxin Ding; Qing-Yu Zhang
Journal:  J Pharmacol Exp Ther       Date:  2015-04-29       Impact factor: 4.030

7.  Glucocorticoid-induced leucine zipper (GILZ) over-expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury.

Authors:  Emanuela Esposito; Stefano Bruscoli; Emanuela Mazzon; Irene Paterniti; Maddalena Coppo; Enrico Velardi; Salvatore Cuzzocrea; Carlo Riccardi
Journal:  Neurotherapeutics       Date:  2012-01       Impact factor: 7.620

8.  Possible involvement of toll-like receptors in the pathogenesis of myasthenia gravis.

Authors:  Yu-Zhong Wang; Mei Yan; Fa-Fa Tian; Jun-Mei Zhang; Qun Liu; Huan Yang; Wen-Bin Zhou; Jing Li
Journal:  Inflammation       Date:  2013-02       Impact factor: 4.092

9.  TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis.

Authors:  Mario Noti; Nadia Corazza; Christoph Mueller; Barbara Berger; Thomas Brunner
Journal:  J Exp Med       Date:  2010-05-03       Impact factor: 14.307

Review 10.  The podocyte as a direct target for treatment of glomerular disease?

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Journal:  Am J Physiol Renal Physiol       Date:  2016-04-20
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