Literature DB >> 12121961

Biguanide-atovaquone synergy against Plasmodium falciparum in vitro.

K Jones1, S A Ward.   

Abstract

The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed. All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro. All of the other compounds tested were either additive or antagonistic.

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Year:  2002        PMID： 12121961      PMCID： PMC127339          DOI： 10.1128/AAC.46.8.2700-2703.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  24 in total

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